Acute disseminated encephalomyelitis: Extremely rare presentation of pediatric human immunodeficiency virus infection.
Acquired human immunodeficiency virus (HIV) infection in a 10-year-old child, presenting with monoparesis, progressing to triplegia over 4 weeks is an extremely rare feature. The child had left upper motor neurone facial palsy with left hemiplegia, paralyzed right lower limb, grade zero power, exagg...
| Publicado en: | Journal of Pediatric Neurosciences Vol. 9; no. 2; pp. 150 - 154 |
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| Autores principales: | , , |
| Formato: | case study diagnostic images Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
May-Aug2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103887955&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103887955 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18171745 1KUH jtl: Journal of Pediatric Neurosciences issn: 18171745 maglogo: N pubinfo: dt: May-Aug2014 vid: 9 iid: 2 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 103887955 98010916 10.4103/1817-1745.139326 NLM25250073 PMC4166840 103887955 ppf: 150 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Acute disseminated encephalomyelitis: Extremely rare presentation of pediatric human immunodeficiency virus infection. aug: au: Patra, Kailash Chandra Shirolkar, Mukund S. Ghane, Vaishali R. affil: Department of Pediatrics, ESI PGIMSR, ESIC Model Hospital, Andheri, Mumbai, Maharashtra, India sug: subj: Encephalomyelitis, Acute Disseminated HIV Infections Symptoms Male Child Child: 6-12 years Male ab: Acquired human immunodeficiency virus (HIV) infection in a 10-year-old child, presenting with monoparesis, progressing to triplegia over 4 weeks is an extremely rare feature. The child had left upper motor neurone facial palsy with left hemiplegia, paralyzed right lower limb, grade zero power, exaggerated deep tendon reflexes and bilateral extensor plantars. Child tested positive for HIV by ELISA. CD3+ absolute count was 431. CD3+ CD4 count was 28, and CD45 absolute count was 478. Magnetic resonance imaging of brain and spine showed multiple ill-defined foci of hyperintensity in white matter suggestive of ADEM. Acute demyelinating encephalomyelitis (ADEM) is an extremely rare presenting feature of perinatally acquired HIV infection in paediatrics. Clinically child remained same even with methylprednisolone, intravenous immunoglobulin, antituberculosis therapy, trimethoprim-sulfamethoxazole prophylaxis and supportive therapy. Child had sudden clinical deterioration and death before antiretroviral therapy could be initiated. This case emphasizes that pediatricians and neurophysicians should suspect HIV as an etiology of ADEM in cases with atypical clinical presentation and social risk factors, in spite of its very rare occurrence. pubtype: Academic Journal doctype: case study diagnostic images Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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