Impact of ICD Artifact Burden on Late Gadolinium Enhancement Cardiac MR Imaging in Patients Undergoing Ventricular Tachycardia Ablation.

Background Cardiac magnetic resonance imaging (CMRI) is the gold standard for myocardial scar evaluation. Although ideal for substrate assessment in ventricular tachycardia (VT), most patients have an implantable cardioverter-defibrillator (ICD) at presentation for ablation. This study evaluates the...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 37; no. 10; pp. 1274 - 1284
Autores principales: Mesubi, Olurotimi, Ahmad, Ghada, Jeudy, Jean, Jimenez, Alejandro, Kuk, Richard, Saliaris, Anastasios, See, Vincent, Shorofsky, Stephen, Dickfeld, Timm
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2014
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Impact of ICD Artifact Burden on Late Gadolinium Enhancement Cardiac MR Imaging in Patients Undergoing Ventricular Tachycardia Ablation.
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        au:
          Mesubi, Olurotimi
          Ahmad, Ghada
          Jeudy, Jean
          Jimenez, Alejandro
          Kuk, Richard
          Saliaris, Anastasios
          See, Vincent
          Shorofsky, Stephen
          Dickfeld, Timm
        affil: Maryland Arrhythmia and Cardiology Imaging Group (MACIG), University of Maryland; Division of Cardiology, University of Maryland; Division of Cardiovascular Medicine, University of Iowa
      sug:
        subj:
          Defibrillators, Implantable
          Contrast Media Therapeutic Use
          Tachycardia, Ventricular Therapy
          Catheter Ablation
          Magnetic Resonance Imaging
          Artifacts
          Therapy, Computer Assisted
          Human
          Descriptive Statistics
          Pretest-Posttest Design
          Maryland
          Academic Medical Centers
          Data Analysis Software
          Chi Square Test
          Middle Age
          Aged
          Male
          Female
          Correlation Coefficient
          Retrospective Design
          Funding Source
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background Cardiac magnetic resonance imaging (CMRI) is the gold standard for myocardial scar evaluation. Although ideal for substrate assessment in ventricular tachycardia (VT), most patients have an implantable cardioverter-defibrillator (ICD) at presentation for ablation. This study evaluates the ICD artifact burden during standard late gadolinium enhancement CMRI (LGE-CMRI) evaluation of myocardial scar in VT patients with ICDs. Methods Thirty-one patients with ICD and cardiomyopathy underwent LGE-CMRI using 1.5-T magnetic resonance scanner before VT ablation. Using the American Heart Association (AHA) 17-segment model, short-axis LGE series were analyzed for artifact burden localization and assessment. Results Preablation CMRI was performed in 31 patients with single chamber (n = 13), dual chamber (n = 11), and biventricular (n = 7) ICDs. Pre- and post-MRI ICD parameters were unchanged. All patients had susceptibility artifact and 51.6% (256 of 496) of segments were affected by artifact. The artifact area (178 ± 136 cm2) resulted in an artifact burden of 54 ± 21% of the LV myocardial area (327 ± 15 cm2). The anterior wall was most affected by artifact (89%) compared with 52%, 49%, and 23% in the lateral, septal, and inferior walls, respectively (P < 0.0001). The apical segments had more artifact burden (66%) than the mid (49%) and basal (44%) segments (P = 0.0005). Artifact area correlated with ICD-heart distance on anteroposterior chest radiograph (r = 0.42, P = 0.021) and body mass index (r = -0.48, P = 0.008). Conclusions Current clinical LGE-CMRI scar imaging protocols produce ICD artifacts that affect >50% of the LV myocardium and correlate with the ICD-heart distance. This significantly limits the application of CMRI for image-guided VT ablation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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