Edoxaban population pharmacokinetics and exposure-response analysis in patients with non-valvular atrial fibrillation.

Purpose: The aim of this study was to evaluate the population pharmacokinetics (PK) and exposure-response relationship of edoxaban in patients with non-valvular atrial fibrillation (AF). Methods: Concentration data from 1,134 subjects in 11 clinical studies (eight phase I, one phase II, and two phas...

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Publicado en:European Journal of Clinical Pharmacology Vol. 70; no. 11; pp. 1339 - 1352
Autores principales: Yin, Ophelia, Tetsuya, Kimura, Miller, Raymond
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Nov2014
Acceso en línea:Ver este registro en EBSCOhost