Adjustment of endogenous concentrations in pharmacokinetic modeling.
Purpose: Estimating pharmacokinetic parameters in the presence of an endogenous concentration is not straightforward as cross-reactivity in the analytical methodology prevents differentiation between endogenous and dose-related exogenous concentrations. This article proposes a novel intuitive modeli...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 70; no. 12; pp. 1465 - 1471 |
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| Autores principales: | , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2014
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| Acceso en línea: | Ver este registro en EBSCOhost |