Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses.

Background: Increasingly, there is a move toward using in vitro toxicity testing to assess human health risk due to chemical exposure. As with in vivo toxicity testing, an important question for in vitro results is whether there are thresholds for adverse cellular responses. Empirical evaluations ma...

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Bibliographic Details
Published in:Environmental Health Perspectives Vol. 122; no. 12; pp. 1261 - 1271
Main Authors: Qiang Zhang, Bhattacharya, Sudin, Conolly, Rory B., Clewell III, Harvey J., Kaminski, Norbert E., Andersen, Melvin E.
Format: tables/charts Journal Article
Published: National Institute of Environmental Health Sciences Dec2014
Online Access:View this record in EBSCOhost