Attitudes of Older Adults to Their Participation in Clinical Trials: A Pilot Study.
Background and objectives: Elderly subjects are still poorly represented in clinical trials, because of unjustified upper age limits. The prejudged reluctance of elderly patients to participate in trials could also be a barrier to their inclusion. The objective of this pilot study was to clarify the...
| Publicado en: | Drugs & Aging Vol. 31; no. 5; pp. 373 - 378 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103935094&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103935094 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1170229X C5B jtl: Drugs & Aging issn: 1170229X maglogo: N pubinfo: dt: May2014 vid: 31 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 103935094 95695235 10.1007/s40266-014-0168-2 NLM24623161 103935094 ppf: 373 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Attitudes of Older Adults to Their Participation in Clinical Trials: A Pilot Study. aug: au: Bloch, Frédéric Charasz, Nathalie affil: Department of Gerontology, Hôpital Broca (Assistance Publique-Hôpitaux de Paris), 54/56 rue Pascal 75013 Paris France sug: subj: Clinical Trials Attitude Research Subjects Human Pilot Studies Surveys Questionnaires Chi Square Test ab: Background and objectives: Elderly subjects are still poorly represented in clinical trials, because of unjustified upper age limits. The prejudged reluctance of elderly patients to participate in trials could also be a barrier to their inclusion. The objective of this pilot study was to clarify the position of elderly subjects on their motivations and the reasons for their ultimate refusal to participate in clinical trials. Method: A questionnaire survey was administered to 150 elderly subjects, aged 70 years or over, living at home, in long-term care units, or hospitalized. Results: Only 44 % of the sample population answered that they would agree to participate in a trial that afforded personal benefit. These results did not depend on age but rather on health condition and sex. Motivations were mostly altruistic rather than based on personal concerns. The main reasons for refusal were fear that the experiment could damage their health and that they thought they were too old. Conclusion: Elderly subjects are not inclined to participate in clinical trials. In the future, we should aim to increase the information on clinical trials for older patients and train researchers appropriately if we wish to increase the participation levels of this age group in such trials. More research is needed on a larger sample. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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