Ototoxicity effects of low exposure to solvent mixture among paint manufacturing workers.
Objective: To evaluate auditory function in a group of workers exposed to organic solvent mixture at a paint factory. Design: Cross-sectional study. Study sample: One hundred and sixty-one workers were studied, 77 exposed to solvents and 84 unexposed. Fourteen solvents were measured, including tolue...
| Publicado en: | International Journal of Audiology Vol. 53; no. 6; pp. 370 - 377 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jun2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103944547&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103944547 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14992027 JW2 jtl: International Journal of Audiology issn: 14992027 maglogo: Y pubinfo: dt: Jun2014 vid: 53 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 103944547 95997591 10.3109/14992027.2014.888597 NLM24684406 103944547 ppf: 370 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Ototoxicity effects of low exposure to solvent mixture among paint manufacturing workers. aug: au: Juárez-Pérez, Cuauhtémoc Arturo Torres-Valenzuela, Arturo Haro-García, Luis Cuauhtémoc Borja-Aburto, Víctor Hugo Aguilar-Madrid, Guadalupe affil: Unidad de Investigación de Salud en el Trabajo, Centro Médico Nacional 'Siglo XXI', Instituto Mexicano del Seguro Social, IMSS, Mexico sug: subj: Ototoxicity Solvents Paint Noise Evoked Potentials, Auditory, Brainstem Audiometry Evaluation Human Linear Regression Blue Collar Workers Cross Sectional Studies Univariate Statistics T-Tests Chi Square Test ab: Objective: To evaluate auditory function in a group of workers exposed to organic solvent mixture at a paint factory. Design: Cross-sectional study. Study sample: One hundred and sixty-one workers were studied, 77 exposed to solvents and 84 unexposed. Fourteen solvents were measured, including toluene, xylene, and n-hexane. Pure-tone audiometry and brainstem auditory-evoked potentials (BAEP) were performed. Industrial noise was < 85 dBA and exposure levels to organic solvents were low. Results: The exposed group showed a hearing impairment in both ears compared with the unexposed workers. Multiple linear regression models adjusted by age, chronic pathologies, and environmental noise for frequency means between 125 and 8000 Hz produced the following results: for the left ear, R2 = 33.3%, exposed vs. unexposed β = 4.1 ( p < 0.001); and for the right ear, R2 = 38%, exposed vs. unexposed β = 4.8 ( p < 0.001). Adjusted for age and chronic pathologies, waves III and V, and interpeak interval latencies were increased (p < 0.05) in both ears in the exposed group. Conclusions: Although solvent mixture concentrations and noise levels were low, our results demonstrate that there may be a concurrent ototoxicity and neurotoxicity condition and emphasize the importance of including BAEP analysis for comprehensive assessments. Future studies that include otoacoustic emissions assessments to monitor cochlear function and central auditory processing tests are imperative. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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