Increased risk of rhinitis symptoms in subjects with gastroesophageal reflux.

Conclusion: This study shows that gastroesophageal reflux and tobacco smoke are associated with adult-onset non-infectious rhinitis (NIR). The results support an association between gastroesophageal reflux and upper airway inflammation. Objectives: To examine the incidence of adult-onset NIR in rela...

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Publicado en:Acta Oto-Laryngologica Vol. 134; no. 6; pp. 615 - 620
Autores principales: Hellgren, Johan, Olin, Anna-Carin, Torén, Kjell
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jun2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2014
      vid: 134
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      pub: Taylor & Francis Ltd
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        atl: Increased risk of rhinitis symptoms in subjects with gastroesophageal reflux.
      aug:
        au:
          Hellgren, Johan
          Olin, Anna-Carin
          Torén, Kjell
        affil: Department of Otorhinolaryngology, Head & Neck Surgery
      sug:
        subj:
          Rhinitis Etiology
          Gastroesophageal Reflux Complications
          Smoking Complications
          Gastroesophageal Reflux Epidemiology
          Human
          Risk Factors
          Male
          Female
          Adult
          Middle Age
          Aged
          Questionnaires
          Odds Ratio
          Confidence Intervals
          Obesity Complications
          Prospective Studies
          Sweden
          Data Analysis Software
          Chi Square Test
          Multiple Regression
          Incidence
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Conclusion: This study shows that gastroesophageal reflux and tobacco smoke are associated with adult-onset non-infectious rhinitis (NIR). The results support an association between gastroesophageal reflux and upper airway inflammation. Objectives: To examine the incidence of adult-onset NIR in relation to several risk factors. Methods: This is a follow-up study of 3307 randomly selected men and women aged 25-75 years from a general population-based sample. At baseline, the subjects were investigated with questionnaires, a pulmonary function test, blood samples, and FENO. At follow-up 4 years later, all the subjects were mailed a respiratory questionnaire. The incidence of NIR and associated risk factors, such as smoking, atopy, asthma, cough, obesity, and gastroesophageal reflux, was assessed. Results: The response rate at follow-up was 92%. The incidence of new-onset NIR was 14.9/1000 person-years ( n = 247). In a regression model including age, gender, obesity, asthma, cough, and atopy, both current smoking (OR 1.7, 95% CI 1.2-2.5, p = 0.002) and gastroesophageal reflux (OR 2.5, 95% CI 1.4-3.1, p < 0.001) were significantly associated with adult-onset NIR.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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