Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.

What is known and objective Both metformin and acarbose are recommended monotherapy and add-on therapy in type 2 diabetes mellitus ( T2 DM). A fixed-dose combination ( FDC) of acarbose and metformin has been developed to reduce pill burden and potentially improve compliance. The current study invest...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of Clinical Pharmacy & Therapeutics Vol. 39; no. 4; pp. 424 - 432
Autores principales:	Kim, S., Jang, I.-J., Shin, D., Shin, D. S., Yoon, S., Lim, K. S., Yu, K.-S., Li, J., Zhang, H., Liu, Y., Brendel, E., Blode, H., Wang, Y.
Formato:	research tables/charts Journal Article
Publicado:	Wiley-Blackwell Aug2014
Acceso en línea:	Ver este registro en EBSCOhost