Echocardiographic Particle Image Velocimetry for the Evaluation of Diastolic Function in Hypertrophic Nonobstructive Cardiomyopathy.

Aims To use particle image velocimetry ( PIV) echocardiography for the evaluation of diastolic dysfunction ( DD) in patients with hypertrophic nonobstructive cardiomyopathy ( HNCM). Methods This study included 50 individuals, thereof 30 patients with DD due to HNCM and 20 healthy individuals who ser...

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Published in:Echocardiography Vol. 31; no. 7; pp. 886 - 895
Main Authors: Prinz, Christian, Lehmann, Roman, Brandao da Silva, Douglas, Jurczak, Barbara, Bitter, Thomas, Faber, Lothar, Horstkotte, Dieter
Format: diagnostic images pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Aug2014
Online Access:View this record in EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Echocardiographic Particle Image Velocimetry for the Evaluation of Diastolic Function in Hypertrophic Nonobstructive Cardiomyopathy.
      aug:
        au:
          Prinz, Christian
          Lehmann, Roman
          Brandao da Silva, Douglas
          Jurczak, Barbara
          Bitter, Thomas
          Faber, Lothar
          Horstkotte, Dieter
        affil: Department of Cardiology, Heart and Diabetes Center NRW, Ruhr-University
      sug:
        subj:
          Cardiomyopathy, Hypertrophic Physiopathology
          Diastole Evaluation
          Rheology Methods
          Echocardiography Methods
          Ventricular Dysfunction, Left Ultrasonography
          Blood Flow Velocity Evaluation
          Human
          Prospective Studies
          Case Control Studies
          Male
          Female
          Middle Age
          Adult
          Algorithms
          Ventricular Dysfunction, Left Classification
          Descriptive Statistics
          Data Analysis Software
          Chi Square Test
          Confidence Intervals
          Spearman's Rank Correlation Coefficient
          Interrater Reliability
          Funding Source
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Male
          Female
      ab: Aims To use particle image velocimetry ( PIV) echocardiography for the evaluation of diastolic dysfunction ( DD) in patients with hypertrophic nonobstructive cardiomyopathy ( HNCM). Methods This study included 50 individuals, thereof 30 patients with DD due to HNCM and 20 healthy individuals who served as controls. HNCM patients were divided into 3 groups according to DD severity. All subjects underwent clinical assessment, exercise testing, and standard as well as PIV echocardiography. Results Energy dissipation was higher in DD patients than in the control group. The severity of flow pattern disturbance corresponded to the degree of DD. In a subgroup of 20 HNCM patients we found significant correlations between invasive measured left ventricular end-diastolic pressure and noninvasive PIV parameters for intraventricular pressure differences and filling. Inter-observer variability (mean difference ± 1.96 SD) for all tested PIV measurements was good. Conclusion According to DD severity, patients with HNCM have disturbed intraventricular flow and reduced intraventricular pressure differences, consistent with a reduced intraventricular suction. PIV echocardiography appears to be feasible for detailed analysis of ventricular vortex flow in DD conditions. Further research using PIV echocardiography in different cardiac pathologies seems warranted.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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