A Method to Noninvasively Identify Cardiac Bioelectrical Sources.
Background We have introduced a method to guide radiofrequency catheter ablation (RCA) procedures that estimates the location of a catheter tip used to pace the ventricles and the target site for ablation using the single equivalent moving dipole (SEMD). Objective To investigate the accuracy of this...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 37; no. 8; pp. 1038 - 1051 |
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| Autores principales: | , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103986410&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103986410 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Aug2014 vid: 37 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 103986410 97427849 10.1111/pace.12380 NLM24645803 103986410 ppf: 1038 ppct: 13 formats: fmt: @attributes: type: P tig: atl: A Method to Noninvasively Identify Cardiac Bioelectrical Sources. aug: au: Sohn, Kwanghyun Lv, Wener Lee, Kichang Galea, Anna Hirschman, Gordon Barrett, Conor Cohen, Richard J. Armoundas, Antonis A. affil: Cardiovascular Research Center, Massachusetts General Hospital sug: subj: Catheter Ablation Noninvasive Procedures Algorithms Heart Diseases Therapy Animal Studies Swine Electrocardiography Data Analysis Software Descriptive Statistics Analysis of Variance Electrodes Heart Ventricle Pathology Confidence Intervals Funding Source ab: Background We have introduced a method to guide radiofrequency catheter ablation (RCA) procedures that estimates the location of a catheter tip used to pace the ventricles and the target site for ablation using the single equivalent moving dipole (SEMD). Objective To investigate the accuracy of this method in resolving epicardial and endocardial electrical sources. Methods Two electrode arrays, each of nine pacing electrodes at known distances from each other, sutured on the left- and right-ventricular (LV and RV) epicardial surfaces of swine, were used to pace the heart at multiple rates, while body surface potentials from 64 sites were recorded and used to estimate the SEMD location. A similar approach was followed for pacing from catheters in the LV and RV. Results The overall (RV & LV) error in estimating the interelectrode distance of adjacent epicardial electrodes was 0.38 ± 0.45 cm. The overall endocardial (RV & LV) interelectrode distance error, was 0.44 ± 0.26 cm. Heart rate did not significantly affect the error of the estimated SEMD location (P > 0.05). The guiding process error became progressively smaller as the SEMD approached an epicardial target site and close to the target, the overall absolute error was ∼0.28 cm. The estimated epicardial SEMD locations preserved their topology in image space with respect to their corresponding physical location of the epicardial electrodes. Conclusion The proposed algorithm suggests one can efficiently and accurately resolve epicardial electrical sources without the need of an imaging modality. In addition, the error in resolving these sources is sufficient to guide RCA procedures. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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