Immediate Effects of Chest Physiotherapy on Hemodynamic, Metabolic, and Oxidative Stress Parameters in Subjects With Septic Shock.
BACKGROUND: Septic shock presents as a continuum of infectious events, generating tissue hypoxia and hypovolemia, and increased oxidative stress. Chest physiotherapy helps reduce secretion, improving dynamic and static compliance, as well as improving secretion clearance and preventing pulmonary com...
| Publicado en: | Respiratory Care Vol. 59; no. 9; pp. 1398 - 1404 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Sep2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103993230&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103993230 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Sep2014 vid: 59 iid: 9 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 103993230 97655478 10.4187/respcare.02859 NLM25006268 103993230 ppf: 1398 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Immediate Effects of Chest Physiotherapy on Hemodynamic, Metabolic, and Oxidative Stress Parameters in Subjects With Septic Shock. aug: au: dos Santos, Rafael S. Donadio, Márcio V. F. da Silva, Gabriela V. Blattner, Clarissa N. Melo, Denizar A. S. Nunes, Fernanda B. Dias, Fernando S. Squizani, Eamim D. Pedrazza, Leonardo Gadegast, Isabella de Oliveira, Jarbas R. affil: Faculdade de Fisioterapia, Hospital São Lucas, Porto Alegre, Rio Grande do Sul, Brazil.; Hospital São Lucas, Porto Alegre, Rio Grande do Sul, Brazil. sug: subj: Physical Therapy Evaluation Shock, Septic Therapy Treatment Outcomes Hemodynamics Metabolism Oxidative Stress Quasi-Experimental Studies Human Adult Middle Age Aged Aged, 80 and Over Descriptive Statistics Models, Statistical Paired T-Tests Wilcoxon Rank Sum Test Male Female Data Analysis Software Parametric Statistics Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: BACKGROUND: Septic shock presents as a continuum of infectious events, generating tissue hypoxia and hypovolemia, and increased oxidative stress. Chest physiotherapy helps reduce secretion, improving dynamic and static compliance, as well as improving secretion clearance and preventing pulmonary complications. The purpose of this study was to evaluate the immediate effect of chest physiotherapy on hemodynamic, metabolic, inflammatory, and oxidative stress parameters in subjects in septic shock. METHODS: We conducted a quasi-experimental study in 30 subjects in septic shock, who underwent chest physiotherapy, without associated heart diseases and with vasopressors < 0.5 μg/kg/min. Venous and arterial blood gases, clinical and hemodynamic data, inflammatory data, lactate, and oxidative stress were evaluated before and 15 min after physiotherapy. RESULTS: Thirty subjects with a mean age of 61.8 ± 15.9 y and Sequential Organ Failure Assessment of 8 (range 6-10) were included. Chest physiotherapy caused a normalization of pH (P = .046) and PaCO2 (P = .008); reduction of lactate (P = .001); and an increase in PaO2 (P = .03), arterial oxygen saturation (P = .02), and PaO2 /FIO2 (P = .034), 15 min after it was applied. CONCLUSIONS: The results indicate that chest physiotherapy has immediate effects, improving oxygenation and reducing lactate and oxidative damage in subjects in septic shock. However, it does not cause alterations in the inflammatory and hemodynamic parameters. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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