Hydroxyapatite and collagen combination-coated dental implants display better bone formation in the peri-implant area than the same combination plus bone morphogenetic protein-2-coated implants, hydroxyapatite only coated implants, and uncoated implants.
PURPOSE: The objective of this study was to compare peri-implant bone formation among uncoated (UC), hydroxyapatite (HA), collagen plus HA (CH), and collagen, HA, plus bone morphogenetic protein-2 (BMP-2) implant groups. MATERIALS AND METHODS: Implants in the UC group had acid-etched surfaces. The s...
| Publicado en: | Journal of Oral & Maxillofacial Surgery (02782391) Vol. 72; no. 1; pp. 53 - 61 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
W B Saunders
Jan2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=103998197&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 103998197 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02782391 1YP jtl: Journal of Oral & Maxillofacial Surgery (02782391) issn: 02782391 maglogo: N pubinfo: dt: Jan2014 vid: 72 iid: 1 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 103998197 103998197 2012437311 10.1016/j.joms.2013.08.031 NLM24331565 103998197 ppf: 53 ppct: 8 formats: tig: atl: Hydroxyapatite and collagen combination-coated dental implants display better bone formation in the peri-implant area than the same combination plus bone morphogenetic protein-2-coated implants, hydroxyapatite only coated implants, and uncoated implants. aug: au: Lee, Sang-Woon Hahn, Byung-Dong Kang, Tae Yeon Lee, Myung-Jin Choi, Je-Yong Kim, Min-Keun Kim, Seong-Gon affil: Fellow, Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea. sug: subj: Biocompatible Materials Bone Morphogenetic Proteins Collagen Dental Implants Minerals Osteogenesis Physiology Prosthesis Design Acid Etching, Dental Methods Aerosols Animal Studies Bone Regeneration Physiology Dental Materials Materials Testing Microscopy, Electron, Scanning Rabbits Spectrophotometry, Infrared Surface Properties Tibia Pathology Tibia Surgery Titanium X-Rays ab: PURPOSE: The objective of this study was to compare peri-implant bone formation among uncoated (UC), hydroxyapatite (HA), collagen plus HA (CH), and collagen, HA, plus bone morphogenetic protein-2 (BMP-2) implant groups. MATERIALS AND METHODS: Implants in the UC group had acid-etched surfaces. The surface coating was applied using the aerosol deposition method. The coated surfaces were examined by scanning electron microscopy, x-ray diffraction (XRD), and Fourier-transformed infrared absorption analysis. Subsequently, 6 implants from each group (total, 24 implants) were installed in the tibias of rabbits. The animals were sacrificed at 6 weeks after implant installation. Peri-implant bone formation and bone-to-implant contact (BIC) were measured in histologic sections. Significant differences among groups were evaluated using analysis of variance. RESULTS: Based on the measured XRD patterns, there was a characteristic HA phase (International Centre for Diffraction Data [ICDD], 086-0740) coated on the titanium (ICDD, 089-3725). Subsequent coating processes for collagen and BMP-2 did not display additional diffraction peaks, but maintained the diffraction patterns of the HA-coated titanium. The presence of collagen was verified by infrared absorption analysis. When comparing these modifications with UC surfaces, only the CH coating displayed significantly greater peri-implant bone formation and BIC (P = .003 and P < .001, respectively). Adding BMP-2 to the implant surface did not produce any advantage compared with the CH coating. CONCLUSIONS: In this study, the CH group displayed significantly greater new bone formation and BIC than the other groups. There was no significant difference among the other groups. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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