Bubble stream reveals functionality of the right-to-left shunt: detection of a potential source for air embolism.

The existence of a right-to-left shunt may increase the likelihood of micro-embolism by allowing a flux of bubbles under hyperbaric conditions. The aim of the study was to measure the relationship between these shunts and bubbles in 10 consecutive subjects using trans-thoracic and trans-esophageal e...

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Publicado en:Ultrasound in Medicine & Biology Vol. 40; no. 2; pp. 330 - 341
Autores principales: Parlak, Ismail Burak, Egi, Salih Murat, Ademoglu, Ahmet, Germonpré, Peter, Esen, Ozlem Batukan, Marroni, Alessandro, Balestra, Costantino
Formato: research Journal Article
Publicado: Elsevier B.V. Feb2014
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Elsevier B.V.
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        10.1016/j.ultrasmedbio.2013.09.019
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        atl: Bubble stream reveals functionality of the right-to-left shunt: detection of a potential source for air embolism.
      aug:
        au:
          Parlak, Ismail Burak
          Egi, Salih Murat
          Ademoglu, Ahmet
          Germonpré, Peter
          Esen, Ozlem Batukan
          Marroni, Alessandro
          Balestra, Costantino
        affil: Institute of Biomedical Engineering, Bogaziçi University, Istanbul, Turkey; Department of Computer Engineering, Galatasaray University, Istanbul, Turkey. Electronic address: bparlak@gsu.edu.tr.
      sug:
        subj:
          Echocardiography Methods
          Embolism, Air Etiology
          Embolism, Air Ultrasonography
          Heart Septal Defects, Atrial Complications
          Heart Septal Defects, Atrial Ultrasonography
          Image Interpretation, Computer Assisted Methods
          Equipment and Supplies
          Adult
          Contrast Media
          Female
          Human
          Male
          Reproducibility of Results
          Sensitivity and Specificity
          Young Adult
          Adult: 19-44 years
          Female
          Male
      ab: The existence of a right-to-left shunt may increase the likelihood of micro-embolism by allowing a flux of bubbles under hyperbaric conditions. The aim of the study was to measure the relationship between these shunts and bubbles in 10 consecutive subjects using trans-thoracic and trans-esophageal echocardiography. In video frames, all cardiac chambers were segmented and bubbles were analyzed by our proposed method and two other methods. The relationship with bubbles and shunts was divided into three classes: no bubbles, 1-20 bubbles, >20 bubbles and measured over 2160 frames. Our sensitivity was 100% and our specificity was between 90.1% and 96.4%. There were 4.32-23.78 bubbles/frame in the left atrium according to our method. After the automatic analysis, shunts were graded double-blinded by two cardiologists. Consequently, we noted that aperture size does not necessarily reflect how active the right-to-left shunt is. Instead, our proposed decay curves constitute a better tool for determining functionality.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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