Performance of rapid tests and algorithms for HIV screening in Abidjan, Ivory Coast.

Seven rapid diagnosis tests (RDTs) of HIV were evaluated by a panel group who collected serum samples from patients in Abidjan (HIV-1 = 203, HIV-2 = 25, HIV-dual = 25, HIV = 305). Kit performances were recorded after the reference techniques (enzyme-linked immunosorbent assay). The following RDTs sh...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of the International Association of Providers of AIDS Care Vol. 13; no. 1; pp. 35 - 40
Autores principales: Loukou, Y G, Cabran, M A, Yessé, Zinzendorf Nanga, Adouko, B M O, Lathro, S J, Agbessi-Kouassi, K B T
Formato: research Journal Article
Publicado: Sage Publications Inc. Jan2014
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Seven rapid diagnosis tests (RDTs) of HIV were evaluated by a panel group who collected serum samples from patients in Abidjan (HIV-1 = 203, HIV-2 = 25, HIV-dual = 25, HIV = 305). Kit performances were recorded after the reference techniques (enzyme-linked immunosorbent assay). The following RDTs showed a sensitivity of 100% and a specificity higher than 99%: Determine, Oraquick, SD Bioline, BCP, and Stat-Pak. These kits were used to establish infection screening strategies. The combination with 2 or 3 of these tests in series or parallel algorithms showed that series combinations with 2 tests (Oraquick and Bioline) and 3 tests (Determine, BCP, and Stat-Pak) gave the best performances (sensitivity, specificity, positive predictive value, and negative predictive value of 100%). However, the combination with 2 tests appeared to be more onerous than the combination with 3 tests. The combination with Determine, BCP, and Stat-Pak tests serving as a tiebreaker could be an alternative to the HIV/AIDS serological screening in Abidjan.