Automated detection of perinatal hypoxia using time-frequency-based heart rate variability features.

Perinatal hypoxia is a cause of cerebral injury in foetuses and neonates. Detection of foetal hypoxia during labour based on the pattern recognition of heart rate signals suffers from high observer variability and low specificity. We describe a new automated hypoxia detection method using time-frequ...

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Publicado en:Medical & Biological Engineering & Computing Vol. 52; no. 2; pp. 183 - 192
Autores principales: Dong, Shiying, Boashash, Boualem, Azemi, Ghasem, Lingwood, Barbara E, Colditz, Paul B
Formato: research Journal Article
Publicado: Springer Nature Feb2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2014
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      pub: Springer Nature
      place: New York, New York
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        atl: Automated detection of perinatal hypoxia using time-frequency-based heart rate variability features.
      aug:
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          Dong, Shiying
          Boashash, Boualem
          Azemi, Ghasem
          Lingwood, Barbara E
          Colditz, Paul B
        affil: UQ Centre for Clinical Research, The University of Queensland, Herston, QLD, Australia, shiying.dong@uqconnect.edu.au.
      sug:
        subj:
          Anoxia Diagnosis
          Heart Rate Physiology
          Signal Processing, Computer Assisted
          Algorithms
          Animal Population Groups
          Animal Studies
          Electrocardiography Methods
          Models, Biological
          Models, Theoretical
          Monitoring, Physiologic
          Sensitivity and Specificity
          Swine
          Time Factors
      ab: Perinatal hypoxia is a cause of cerebral injury in foetuses and neonates. Detection of foetal hypoxia during labour based on the pattern recognition of heart rate signals suffers from high observer variability and low specificity. We describe a new automated hypoxia detection method using time-frequency analysis of heart rate variability (HRV) signals. This approach uses features extracted from the instantaneous frequency and instantaneous amplitude of HRV signal components as well as features based on matrix decomposition of the signals' time-frequency distributions using singular value decomposition and non-negative matrix factorization. The classification between hypoxia and non-hypoxia data is performed using a support vector machine classifier. The proposed method is tested on a dataset obtained from a newborn piglet model with a controlled hypoxic insult. The chosen HRV features show strong performance compared to conventional spectral features and other existing methods of hypoxia detection with a sensitivity 93.3 %, specificity 98.3 % and accuracy 95.8 %. The high predictive value of this approach to detecting hypoxia is a substantial step towards developing a more accurate and reliable hypoxia detection method for use in human foetal monitoring.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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