Development of a Software for Quantitative Evaluation Radiotherapy Target and Organ-at-Risk Segmentation Comparison.

Modern radiotherapy requires accurate region of interest (ROI) inputs for plan optimization and delivery. Target delineation, however, remains operator-dependent and potentially serves as a major source of treatment delivery error. In order to optimize this critical, yet observer-driven process, a f...

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Publicado en:Journal of Digital Imaging Vol. 27; no. 1; pp. 108 - 120
Autores principales: Kalpathy-Cramer, Jayashree, Awan, Musaddiq, Bedrick, Steven, Rasch, Coen, Rosenthal, David, Fuller, Clifton
Formato: diagnostic images equations & formulas pictorial tables/charts Journal Article
Publicado: Springer Nature Feb2014
Acceso en línea:Ver este registro en EBSCOhost
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          Kalpathy-Cramer, Jayashree
          Awan, Musaddiq
          Bedrick, Steven
          Rasch, Coen
          Rosenthal, David
          Fuller, Clifton
        affil: Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Department of Radiology and Neuroscience, Massachusetts General Hospital, Charlestown USA
      sug:
        subj:
          Software Design
          Radiotherapy, Computer-Assisted
          Website Development
          Teaching Methods
          Algorithms
          Medical Informatics
      ab: Modern radiotherapy requires accurate region of interest (ROI) inputs for plan optimization and delivery. Target delineation, however, remains operator-dependent and potentially serves as a major source of treatment delivery error. In order to optimize this critical, yet observer-driven process, a flexible web-based platform for individual and cooperative target delineation analysis and instruction was developed in order to meet the following unmet needs: (1) an open-source/open-access platform for automated/semiautomated quantitative interobserver and intraobserver ROI analysis and comparison, (2) a real-time interface for radiation oncology trainee online self-education in ROI definition, and (3) a source for pilot data to develop and validate quality metrics for institutional and cooperative group quality assurance efforts. The resultant software, Target Contour Testing/Instructional Computer Software (TaCTICS), developed using Ruby on Rails, has since been implemented and proven flexible, feasible, and useful in several distinct analytical and research applications.
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        equations & formulas
        pictorial
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