Assessment of Central Airway Obstruction Using Impulse Oscillometry Before and After Interventional Bronchoscopy.
BACKGROUND: Spirometry is used to physiologically assess patients with central airway obstruction (CAO) before and after interventional bronchoscopy, but is not always feasible in these patients, does not localize the anatomic site of obstruction, and may not correlate with the patient's functional...
| Publicado en: | Respiratory Care Vol. 59; no. 2; pp. 231 - 241 |
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| Autores principales: | , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Feb2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104015733&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104015733 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Feb2014 vid: 59 iid: 2 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 104015733 94081262 10.4187/respcare.02094 NLM23882104 104015733 ppf: 231 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Assessment of Central Airway Obstruction Using Impulse Oscillometry Before and After Interventional Bronchoscopy. aug: au: Hiroshi Handa Jyongsu Huang Murgu, Septimiu D. Masamichi Mineshita Noriaki Kurimoto Colt, Henri G. Teruomi Miyazawa affil: Division of Respiratory and Infectious Diseases, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa, Japan sug: subj: Airway Obstruction Diagnosis Oscilloscope Utilization Bronchoscopy Spirometry Methods Human Pretest-Posttest Design Respiratory Function Tests Japan Tomography, X-Ray Computed Methods Dyspnea Descriptive Statistics Female Male Data Analysis Software Mann-Whitney U Test Wilcoxon Signed Rank Test Spearman's Rank Correlation Coefficient Middle Age Aged Middle Aged: 45-64 years Aged: 65+ years Female Male ab: BACKGROUND: Spirometry is used to physiologically assess patients with central airway obstruction (CAO) before and after interventional bronchoscopy, but is not always feasible in these patients, does not localize the anatomic site of obstruction, and may not correlate with the patient's functional impairment. Impulse oscillometry may overcome these limitations. We assessed the correlations between impulse oscillometry measurements, symptoms, and type of airway narrowing, before and after interventional bronchoscopy, and whether impulse oscillometry parameters can discriminate between fixed and dynamic CAO. METHODS: Twenty consecutive patients with CAO underwent spirometry, impulse oscillometry, computed tomography, dyspnea assessment, and bronchoscopy, before and after interventional bronchoscopy. The collapsibility index (the percent difference in airway lumen diameter during expiration versus during inspiration) was calculated using morphometric bronchoscopic images during quiet breathing. Variable CAO was defined as a collapsibility index of > 50%. Fixed CAO was defined as a collapsibility index of < 50%. The degree of obstruction was analyzed with computed tomography measurements. RESULTS: After interventional bronchoscopy, all impulse oscillometry measurements significantly improved, especially resistance at 5 Hz, which decreased from 0.67 ± 0.29kPa/L/s to 0.38 0.17kPa/L/s (P < .001), and reactance at 20 Hz, which increased from −0.09 ± 0.11 to 0.03 ± 0.08 (P < .001). Changes in dyspnea score correlated with resistance at 5 Hz, the difference between the resistance at 5 Hz and the resistance at 20 Hz, and the reactance at 5 Hz, but not with spirometry measurements. The type of obstruction also correlated with dyspnea score, and showed distinct impulse oscillometry measurements. CONCLUSIONS: Impulse oscillometry measurements correlate with symptom improvements after interventional bronchoscopy. Impulse oscillometry might be useful to discriminate variable from fixed central airway obstruction. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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