Phosphodiesterase inhibition facilitates cognitive restoration in rodent models of age-related memory decline.
BACKGROUND: Previous studies have shown that cyclic nucleotide phosphodiesterase type 5 (PDE5) inhibition with the drugs sildenafil and vardenafil can enhance spatial performance and object recognition in rodent models of learning and memory. OBJECTIVE: We review recent studies on PDE5 inhibition an...
| Publicado en: | NeuroRehabilitation Vol. 34; no. 1; pp. 101 - 112 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |