Urinary stone detection and characterisation with dual-energy CT urography after furosemide intravenous injection: preliminary results.

Objectives: To investigate the added advantage of IV furosemide injection and the subsequent urine dilution in the detection of urinary calculi in the excretory phase of dual-source dual-energy (DE) computed tomography (CT) urography, and to investigate the feasibility of characterising the calculi...

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Publicado en:European Radiology Vol. 24; no. 3; pp. 709 - 715
Autores principales: Botsikas, Diomidis, Hansen, Catrina, Stefanelli, Salvatore, Becker, Christoph D, Montet, Xavier
Formato: research Journal Article
Publicado: Springer Nature Mar2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2014
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      pub: Springer Nature
      place: New York, New York
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        atl: Urinary stone detection and characterisation with dual-energy CT urography after furosemide intravenous injection: preliminary results.
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          Botsikas, Diomidis
          Hansen, Catrina
          Stefanelli, Salvatore
          Becker, Christoph D
          Montet, Xavier
        affil: Radiology Department, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland, diomidis.botsikas@hcuge.ch.
      sug:
        subj:
          Furosemide Diagnostic Use
          Tomography, X-Ray Computed Methods
          Urinary Calculi Radiography
          Urography Methods
          Adult
          Aged
          Aged, 80 and Over
          Contrast Media
          Diuretics Administration and Dosage
          Diuretics Diagnostic Use
          Pilot Studies
          Female
          Furosemide Administration and Dosage
          Human
          Injections, Intravenous
          Male
          Middle Age
          Radiation Dosage
          Retrospective Design
          Urinary Calculi Urine
          Young Adult
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objectives: To investigate the added advantage of IV furosemide injection and the subsequent urine dilution in the detection of urinary calculi in the excretory phase of dual-source dual-energy (DE) computed tomography (CT) urography, and to investigate the feasibility of characterising the calculi through diluted urine.Methods: Twenty-three urinary calculi were detected in 116 patients who underwent DECT urography for macroscopic haematuria with a split bolus two- or three-acquisition protocol, including a true unenhanced series and at least a mixed nephrographic excretory phase. Virtual unenhanced images were reconstructed from contrast-enhanced DE data. Calculi were recorded on all series and characterised based on their X-ray absorption characteristics at 100 kVp and 140 kVp in both true unenhanced and nephrographic excretory phase series.Results: All calculi with a diameter more than 2 mm were detected in the virtual unenhanced phase and in the nephrographic excretory phase. Thirteen of these calculi could be characterised in the true unenhanced phase and in the mixed nephrographic excretory phase. The results were strictly identical for both phases, six of them being recognised as non-uric acid calculi and seven as uric acid calculi.Conclusions: Mixed nephrographic excretory phase DECT after furosemide administration allows both detection and characterisation of clinically significant calculi, through the diluted urine.Key Points: • Urinary tract stones can be detected on excretory phase through diluted urine. • Urinary tract stone characterisation with dual-energy CT (DECT) is possible through diluted urine. • A dual energy split-bolus CT urography simultaneously enables urinary stone detection and characterisation.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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