Quantitative Magnetic Resonance Imaging Analysis of the Relationship Between Contact Force and Left Atrial Scar Formation After Catheter Ablation of Atrial Fibrillation.
Left Atrial Scar Formation After Contact Force-Guided AF Ablation Background Catheter contact force (CF) is an important determinant of radiofrequency (RF) lesion quality during pulmonary vein isolation (PVI). Late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) allows good visualizati...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 25; no. 2; pp. 138 - 146 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Feb2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104023637&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104023637 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Feb2014 vid: 25 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104023637 94397696 10.1111/jce.12298 NLM24118197 104023637 ppf: 138 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Quantitative Magnetic Resonance Imaging Analysis of the Relationship Between Contact Force and Left Atrial Scar Formation After Catheter Ablation of Atrial Fibrillation. aug: au: Sohns, Christian Karim, Rashed Harrison, James Arujuna, Aruna Linton, Nick Sennett, Richard Lambert, Hendrik Leo, Giovanni Williams, Steven Razavi, Reza Wright, Matt Schaeffter, Tobias O'neill, Mark Rhode, Kawal affil: Division of Imaging Sciences and Biomedical Engineering, King's College London; Department of Cardiology and Pneumology, Heart Center, Georg-August-University of Göttingen sug: subj: Magnetic Resonance Imaging Catheter Ablation Adverse Effects Atrial Fibrillation Cicatrix Diagnosis Heart Atrium, Left Pathology Human Descriptive Statistics Prospective Studies Data Analysis Software Male Female Middle Age T-Tests Chi Square Test Fisher's Exact Test Funding Source Middle Aged: 45-64 years Male Female ab: Left Atrial Scar Formation After Contact Force-Guided AF Ablation Background Catheter contact force (CF) is an important determinant of radiofrequency (RF) lesion quality during pulmonary vein isolation (PVI). Late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) allows good visualization of ablation lesions. Objective This study describes a new technique to examine the relationship between CF during RF delivery and LGE signal intensity (SI) following PVI. Methods Six patients underwent PVI for paroxysmal AF using a CF-sensing catheter and following preprocedural MRI. During ablation, CF-time integral (FTI) and position was documented for each RF application. All patients underwent repeat LGE MRI 3 months later. The LGE SIs were projected onto a MRI-derived 3-dimensional left atrial (LA) shell and a CF map was generated on the same shell. The entire LA surface was divided into 5 mm2 segments. Force and LGE maps were fused and compared for each 5 mm2 zone. An effective lesion was defined when MRI-defined scar occupied >90% of a 5 mm2 analysis zone. Results Acute PVI was achieved in 100%. Two hundred sixty-eight RF lesions were tagged on the LA shells and given a lesion-specific FTI. Increasing FTI correlated with increased LGE SI, which was greater when the FTI was > 1,200 gs. Below an FTI of 1,200 gs, an increment in the FTI resulted in only a small increment in scar, whereas above 1,200 gs an increment in the FTI resulted in a large change of scar. Conclusion There is a correlation between FTI and LGE SI in MRI following AF ablation. Real-time FTI maps are feasible and may prevent inadequate lesion formation. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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