Can Experienced Observers Differentiate between Lipoma and Well-Differentiated Liposarcoma Using Only MRI?
Well-diferentiated liposarcoma represents a radiographic diagnostic dilemma. To determine the accuracy, interrater reliability, and relationship of stranding, nodularity, and size in the MRI differentiation of lipoma and well-differentiated liposarcoma, MRI scans of 60 patients with large (>5 cm), d...
| Publicado en: | Sarcoma pp. 1 - 7 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104033811&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104033811 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1357714X 57R jtl: Sarcoma issn: 1357714X maglogo: Y pubinfo: dt: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104033811 104033811 2012487754 NLM24385845 PMC3872425 104033811 ppf: 1 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Can Experienced Observers Differentiate between Lipoma and Well-Differentiated Liposarcoma Using Only MRI? aug: au: O'Donnell, Patrick W. Griffin, Anthony M. Eward, William C. Sternheim, Amir White, Lawrence M. Wunder, Jay S. Ferguson, Peter C. affil: Department of Orthopaedic Surgery, Markey Cancer Center, University of Kentucky, 740S. Limestone Avenue, Lexington, KY 40536, USA sug: subj: Lipoma Diagnosis Liposarcoma Diagnosis Diagnosis, Differential Magnetic Resonance Imaging Human Validity Interrater Reliability Descriptive Statistics Confidence Intervals kappa Statistic Data Analysis Software Reliability ab: Well-diferentiated liposarcoma represents a radiographic diagnostic dilemma. To determine the accuracy, interrater reliability, and relationship of stranding, nodularity, and size in the MRI differentiation of lipoma and well-differentiated liposarcoma, MRI scans of 60 patients with large (>5 cm), deep, pathologically proven lipomas or well-differentiated liposarcomas were examined by 10 observers with subspecialty training blinded to diagnosis. Observers indicated whether the amount of stranding, nodularity, and size of each tumor suggested a benign or malignant diagnosis and rendered a diagnosis of lipoma or well-differentiated liposarcoma. he accuracy, reliability, and relationship of stranding, nodularity, and size to diagnosis were calculated for all samples. 69% of reader MRI diagnoses agreed with final pathology diagnosis (95% CI 65-73%). Readers tended to err choosing a diagnosis of liposarcoma, correctly identifying lipomas in 63% of cases (95% CI 58-69%) and liposarcomas in 75% of cases (95% CI 69-80%). Assessment of the relationship of stranding, nodularity, and size to correct diagnosis showed that the presence of each was associated with a decreased likelihood of a lipoma pathological diagnosis (P < 0.01). While the radiographic diagnosis of lipoma or well-differentiated liposarcoma cannot be made with 100% certainty, experienced observers have a 69% chance of rendering a correct diagnosis. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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