Idiopathic eosinophilic pneumonia in children: the French experience.
Background: Idiopathic eosinophilic pneumonia is extremely rare in children and adults. We present herein the first series describing the specificities of idiopathic chronic (ICEP) and acute (IAEP) eosinophilic pneumonia in children.Methods: We retrospectively analyzed all cases of ICEP and IAEP in...
| Publicado en: | Orphanet Journal of Rare Diseases Vol. 9; no. 1; pp. 28 - 29 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104036222&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104036222 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17501172 38NP jtl: Orphanet Journal of Rare Diseases issn: 17501172 maglogo: N pubinfo: dt: 2014 vid: 9 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 104036222 104036222 NLM24555756 2012493662 10.1186/1750-1172-9-28 NLM24555756 PMC3937523 104036222 ppf: 28 ppct: 1 formats: tig: atl: Idiopathic eosinophilic pneumonia in children: the French experience. aug: au: Giovannini-Chami, Lisa Hadchouel, Alice Nathan, Nadia Brémont, Francois Dubus, Jean-Christophe Fayon, Michael Houdouin, Véronique Berlioz-Baudoin, Michèle Feret, Virginie Leblanc, Thierry Morelle, Karine Albertini, Marc Clement, Annick de Blic, Jacques affil: Pediatric Pulmonology and Allergy Department, Hôpitaux pédiatriques de Nice CHU-Lenval, Nice F-06200, France. giovannini-chami.l@pediatrie-chulenval-nice.fr. sug: subj: Pulmonary Eosinophilia Physiopathology Adolescence Body Fluids Child Child, Preschool Female France Human Male Pulmonary Eosinophilia Drug Therapy Pulmonary Eosinophilia Epidemiology Pulmonary Eosinophilia Radiography Retrospective Design Tomography, X-Ray Computed Methods Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Female Male ab: Background: Idiopathic eosinophilic pneumonia is extremely rare in children and adults. We present herein the first series describing the specificities of idiopathic chronic (ICEP) and acute (IAEP) eosinophilic pneumonia in children.Methods: We retrospectively analyzed all cases of ICEP and IAEP in children that were retrieved from French Reference Centers for rare pediatric lung diseases.Results: Five cases of pediatric ICEP were identified. Corticosteroid or immunosuppressive therapy dramatically improved the outcome in three cases. The remaining two cases had a persistent interstitial pattern with progressive development of cystic airspace lesions. Three cases of IAEP in adolescents were reported, with one requiring four days of extracorporeal membrane oxygenation.Conclusion: ICEP is a rare disease with a polymorphic clinical presentation in children. We identified patients with persistent interstitial patterns progressing to cystic airspace regions, for which the boundaries with idiopathic interstitial pneumonias are difficult to establish. We therefore propose a specific pediatric definition and classification algorithm. IAEP in children remains an inflammatory reaction of the lung to an acute toxic exposure, mainly tobacco, as in adults. International studies are required to comprehensively assess the various clinical forms of the disease as well as the appropriate therapeutic regimens. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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