Endoscopic findings in uninvestigated dyspepsia.
Background: It is important to know the causes of dyspepsia to establish the therapeutic approach. Dyspepsia is a frequent syndrome in our country, where there are restrictions to endoscopy and high prevalence of Helicobacter pylori (H. pylori) infection. This study aimed to assess the endoscopic fi...
| Publicado en: | BMC Gastroenterology Vol. 14; no. 1; pp. 19 - 20 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104036362&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104036362 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1471230X 1CHO jtl: BMC Gastroenterology issn: 1471230X maglogo: N pubinfo: dt: 2014 vid: 14 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 104036362 104036362 NLM24499444 2012493942 10.1186/1471-230X-14-19 NLM24499444 PMC3938027 104036362 ppf: 19 ppct: 1 formats: tig: atl: Endoscopic findings in uninvestigated dyspepsia. aug: au: Faintuch, Jacob Jehuda Silva, Fernando Marcuz Navarro-Rodriguez, Tomás Barbuti, Ricardo Correa Hashimoto, Claudio Lyoiti Rossini, Alessandra Rita Asayama Lopes Diniz, Marcio Augusto Eisig, Jaime Natan affil: Division of Clinical Medicine and Propaedeutic Clinic of Hospital das Clínicas da Faculdade de Medicina da USP, Sao Paulo, Brasil. faintuch@zipmail.com.br. sug: subj: Dyspepsia Diagnosis Dyspepsia Etiology Endoscopy, Gastrointestinal Esophageal Neoplasms Complications Helicobacter Infections Complications Stomach Diseases Complications Adolescence Adult Aged Aged, 80 and Over Brazil Breath Tests Duodenal Ulcer Complications Female Gastroesophageal Reflux Complications Helicobacter Pylori Human Male Middle Age Prospective Studies Questionnaires Urease Analysis Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Background: It is important to know the causes of dyspepsia to establish the therapeutic approach. Dyspepsia is a frequent syndrome in our country, where there are restrictions to endoscopy and high prevalence of Helicobacter pylori (H. pylori) infection. This study aimed to assess the endoscopic findings of the syndrome, in an outpatient screening clinic of a tertiary hospital in São Paulo.Methods: Outpatients with uninvestigated dyspepsia, according to Rome III criteria, answered a dyspepsia questionnaire and underwent esophagogastroduodenoscopy. The Rapid Urease Test was applied to fragments of the antral mucosa and epidemiological data were collected from the studied population. Organic dyspepsia findings were analyzed with different variables to verify statistically significant associations.Results: Three hundred and six patients were included and 282 were analyzed in the study. The mean age was 44 years and women comprised 65% of the sample. Forty-five percent of the patients reported alarm symptoms. Functional dyspepsia was found in 66% of the patients (20% with normal endoscopy results and 46% with gastritis), 18% had GERD and 13% had ulcers (duodenal in 9% and gastric in 4%). Four cases of gastric adenocarcinoma were identified (1.4%), one without alarm characteristics, 1 case of adenocarcinoma of the distal esophagus and 1 case of gastric lymphoma. The prevalence of H. pylori was 54% and infection, age and smoking status were associated with organic dyspepsia. The age of 48 years was indicative of alarm signs.Conclusions: The endoscopic diagnosis of uninvestigated dyspepsia in our setting showed a predominance of functional disease, whereas cancer was an uncommon finding, despite the high prevalence of H. pylori. Organic dyspepsia was associated with infection, age and smoking status. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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