Correlation Between Spirometry Values and Pulmonary Artery Pressure in Young Healthy Subjects.

BACKGROUND: Pulmonary hypertension is frequently associated with parenchymal lung disease. We evaluated the association between spirometry values and pulmonary artery systolic pressure (PASP) in young subjects without lung disease METHODS: We studied applicants to the Israeli Air Force, who undergo...

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Publicado en:Respiratory Care Vol. 59; no. 3; pp. 371 - 375
Autores principales: Grossman, Alon, Benderly, Michal, Prokupetz, Alex, Gordon, Barak, Kalter-Leibovici, Ofra
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Mar2014
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Correlation Between Spirometry Values and Pulmonary Artery Pressure in Young Healthy Subjects.
      aug:
        au:
          Grossman, Alon
          Benderly, Michal
          Prokupetz, Alex
          Gordon, Barak
          Kalter-Leibovici, Ofra
        affil: Israeli Air Force Aero Medical Center, Tel Hashomer, Israel; Department of Internal Medicine E, Rabin Medical Center, Beilinson Campus affiliated to Tel Aviv University Sackler Medical School, Petah Tikva, Israel
      sug:
        subj:
          Spirometry
          Pulmonary Wedge Pressure
          Human
          Israel
          Echocardiography
          Respiratory Function Tests
          Descriptive Statistics
          Male
          Female
          Adolescence
          Hypertension, Pulmonary Pathology
          Military Personnel
          Spearman's Rank Correlation Coefficient
          Retrospective Design
          Record Review
          Adolescent: 13-18 years
          Male
          Female
      ab: BACKGROUND: Pulmonary hypertension is frequently associated with parenchymal lung disease. We evaluated the association between spirometry values and pulmonary artery systolic pressure (PASP) in young subjects without lung disease METHODS: We studied applicants to the Israeli Air Force, who undergo routine evaluation that includes resting spirometry and echocardiography. Applicants with overt lung disease were excluded. All echocardiographic studies performed in the years 1994 through 2010 (n = 6,598) were screened, and files that included PASP and spirometry values were analyzed for the association between PASP and FVC, FEV1, FEV1/FVC, peak expiratory flow, and forced expiratory flow during the middle half of the FVC maneuver. RESULTS: Of the 647 air force applicants who underwent echocardiography in which PASP was measurable and had spirometry data, 607 (94%) were male, and their average age was 18.16 ± 0.73 years. Mean PASP was 26.4 ± 5.2 mm Hg (range 10–41 mm Hg). None of the spirometry values significantly correlated with PASP. CONCLUSIONS: PASP in young healthy subjects is not significantly associated with spirometry values. Lung mechanics probably do not contribute significantly to PASP in this population.
      pubtype: Academic Journal
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        research
        tables/charts
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      ougenre: Article
    language: English
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