The Clinical Spectrum and Antibiotic Sensitivity Patterns of Staphylococcal Pyodermas in the Community and Hospital.
Context: The uncontrolled use of antibiotics has resulted in a relentless spread of multiresistant strains of Staphylococcus aureus. There are studies conducted in medical colleges in Chandigarh, Chennai, Mumbai and Vellore comparing pyodermas in the community and hospital setting based on clinical...
| Publicado en: | Indian Journal of Dermatology Vol. 59; no. 2; pp. 143 - 151 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Mar/Apr2014
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104041947&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104041947 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00195154 259H jtl: Indian Journal of Dermatology issn: 00195154 maglogo: N pubinfo: dt: Mar/Apr2014 vid: 59 iid: 2 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 104041947 94765803 10.4103/0019-5154.127674 NLM24700932 104041947 ppf: 143 ppct: 8 formats: tig: atl: The Clinical Spectrum and Antibiotic Sensitivity Patterns of Staphylococcal Pyodermas in the Community and Hospital. aug: au: Furtado, Shireen Bhat, Ramesh M. Rekha, B. Sukumar, D. Kamath, Ganesh H. Martis, Jacintha Nandakishore, B. affil: Departments of Dermatology, Venereology and Leprology, Fr. Muller Medical College, Mangalore, Karnataka, India. sug: subj: Staphylococcal Infections Diagnosis Pyoderma Diagnosis Staphylococcal Infections Drug Therapy Methicillin-Resistant Staphylococcus Aureus Human Time Factors Communities Hospitals Microbial Culture and Sensitivity Tests Data Analysis Software T-Tests ab: Context: The uncontrolled use of antibiotics has resulted in a relentless spread of multiresistant strains of Staphylococcus aureus. There are studies conducted in medical colleges in Chandigarh, Chennai, Mumbai and Vellore comparing pyodermas in the community and hospital setting based on clinical and bacteriological parameters. Aims: This study, conducted over 1½ years from March 2009 to August 2010, aimed at analyzing the clinical spectrum and antibiotic sensitivity pattern of community and hospital-associated (HA) staphylococcal pyoderma. It also assessed the prevalence of methicillin-resistant S. aureus (MRSA) in the community and hospital cohort settings. Subjects and Methods: The study comprised of 200 cases of staphylococcal pyodermas, derived from the community (150 cases) and hospital (50 cases). Patients were evaluated based on their clinical presentation; antibiotic susceptibility was tested using the Kirby-Bauer disk diffusion method. Statistical Analysis Used: Statistical significance between individual attributes between the community and HA staphylococcal pyoderma groups was analyzed using Chi-square test and mean differences using student's t-test. Results: Factors associated with community-associated (CA) pyodermas were young age (P = 0.0021), primary pyodermas, and involvement of extremities, while those with HA pyodermas were middle age, secondary pyodermas, and significantly increased body surface involvement (P = 0.041). Incidence of CA-MRSA was 11.3%, while that of HA-MRSA was 18%. Conclusions: A high level of resistance to first-line drugs such as penicillin, ciprofloxacin and cotrimoxazole was observed, more so in the hospital strain than in the community strain. S. aureus demonstrated good susceptibility to cephalosporins. Though the two strains of MRSA differed clinically, they showed 100% sensitivity to vancomycin and linezolid. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|