Estimating the measles effective reproduction number in Australia from routine notification data.

Objective To estimate the measles effective reproduction number (R) in Australia by modelling routinely collected notification data. Methods R was estimated for 2009-2011 by means of three methods, using data from Australia's National Notifiable Disease Surveillance System. Method 1 estimated R as 1...

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Publicado en:Bulletin of the World Health Organization Vol. 92; no. 3; pp. 171 - 178
Autores principales: May Chiew, Gidding, Heather F., Dey, Aditi, Wood, James, Martin, Nicolee, Davis, Stephanie, McIntyre, Peter
Formato: research tables/charts Journal Article
Publicado: World Health Organization Mar2014
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Estimating the measles effective reproduction number in Australia from routine notification data.
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        au:
          May Chiew
          Gidding, Heather F.
          Dey, Aditi
          Wood, James
          Martin, Nicolee
          Davis, Stephanie
          McIntyre, Peter
        affil: National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children¿s Hospital Westmead, Sydney, Australia.
      sug:
        subj:
          Measles Epidemiology
          Disease Surveillance Methods
          Disease Outbreaks Australia
          Human
          Funding Source
          Australia
          Data Analysis Software
          Confidence Intervals
          Epidemiological Research
          Descriptive Statistics
          Child
          Adolescence
          Adult
          Infection Control
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
      ab: Objective To estimate the measles effective reproduction number (R) in Australia by modelling routinely collected notification data. Methods R was estimated for 2009-2011 by means of three methods, using data from Australia's National Notifiable Disease Surveillance System. Method 1 estimated R as 1 ? P, where P equals the proportion of cases that were imported, as determined from data on place of acquisition. The other methods estimated R by fitting a subcritical branching process that modelled the spread of an infection with a given R to the observed distributions of outbreak sizes (method 2) and generations of spread (method 3). Stata version 12 was used for method 2 and Matlab version R2012 was used for method 3. For all methods, calculation of 95% confidence intervals (CIs) was performed using a normal approximation based on estimated standard errors. Findings During 2009-2011, 367 notifiable measles cases occurred in Australia (mean annual rate: 5.5 cases per million population). Data were 100% complete for importation status but 77% complete for outbreak reference number. R was estimated as < 1 for all years and data types, with values of 0.65 (95% CI: 0.60-0.70) obtained by method 1, 0.64 (95% CI: 0.56-0.72) by method 2 and 0.47 (95% CI: 0.38-0.57) by method 3. Conclusion The fact that consistent estimates of R were obtained from all three methods enhances confidence in the validity of these methods for determining R.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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