Level Set Segmentation of Breast Masses in Contrast-Enhanced Dedicated Breast CT and Evaluation of Stopping Criteria.
Dedicated breast CT (bCT) produces high-resolution 3D tomographic images of the breast, fully resolving fibroglandular tissue structures within the breast and allowing for breast lesion detection and assessment in 3D. In order to enable quantitative analysis, such as volumetrics, automated lesion se...
| Published in: | Journal of Digital Imaging Vol. 27; no. 2; pp. 237 - 248 |
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| Main Authors: | , , , , , , |
| Format: | diagnostic images research tables/charts Journal Article |
| Published: |
Springer Nature
Apr2014
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104043770&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104043770 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Apr2014 vid: 27 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104043770 94852777 10.1007/s10278-013-9652-1 NLM24162667 PMC3948924 104043770 ppf: 237 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Level Set Segmentation of Breast Masses in Contrast-Enhanced Dedicated Breast CT and Evaluation of Stopping Criteria. aug: au: Kuo, Hsien-Chi Giger, Maryellen Reiser, Ingrid Boone, John Lindfors, Karen Yang, Kai Edwards, Alexandra affil: Department of Radiology, The University of Chicago, 5841 S. Maryland Avenue MC2026 Chicago 60637 USA sug: subj: Breast Radiography Tomography, X-Ray Computed Diagnosis, Computer Assisted Radiographic Image Enhancement Methods Radiographic Image Interpretation, Computer-Assisted Methods Contrast Media Algorithms Evaluation Research Human Funding Source ab: Dedicated breast CT (bCT) produces high-resolution 3D tomographic images of the breast, fully resolving fibroglandular tissue structures within the breast and allowing for breast lesion detection and assessment in 3D. In order to enable quantitative analysis, such as volumetrics, automated lesion segmentation on bCT is highly desirable. In addition, accurate output from CAD (computer-aided detection/diagnosis) methods depends on sufficient segmentation of lesions. Thus, in this study, we present a 3D lesion segmentation method for breast masses in contrast-enhanced bCT images. The segmentation algorithm follows a two-step approach. First, 3D radial-gradient index segmentation is used to obtain a crude initial contour, which is then refined by a 3D level set-based active contour algorithm. The data set included contrast-enhanced bCT images from 33 patients containing 38 masses (25 malignant, 13 benign). The mass centers served as input to the algorithm. In this study, three criteria for stopping the contour evolution were compared, based on (1) the change of region volume, (2) the average intensity in the segmented region increase at each iteration, and (3) the rate of change of the average intensity inside and outside the segmented region. Lesion segmentation was evaluated by computing the overlap ratio between computer segmentations and manually drawn lesion outlines. For each lesion, the overlap ratio was averaged across coronal, sagittal, and axial planes. The average overlap ratios for the three stopping criteria ranged from 0.66 to 0.68 (dice coefficient of 0.80 to 0.81), indicating that the proposed segmentation procedure is promising for use in quantitative dedicated bCT analyses. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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