Clinical effect of bovine amniotic membrane and hydrocolloid on wound by laser treatment: Prospective comparative randomized clinical trial.
Bovine amniotic membrane ( BAM) has been regarded as an ideal dressing material because it accelerates epithelization and has anti-inflammatory, anti-angiogenic, and strong analgesic effects. To evaluate the clinical effects of BAM and compare them to that of hydrocolloid dressings on wounds created...
| Publicado en: | Wound Repair & Regeneration Vol. 22; no. 2; pp. 212 - 220 |
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| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
Mar/Apr2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104048684&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104048684 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10671927 DPV jtl: Wound Repair & Regeneration issn: 10671927 maglogo: Y pubinfo: dt: Mar/Apr2014 vid: 22 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104048684 94956205 10.1111/wrr.12145 NLM24635171 104048684 ppf: 212 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Clinical effect of bovine amniotic membrane and hydrocolloid on wound by laser treatment: Prospective comparative randomized clinical trial. aug: au: Min, Seonguk Yoon, Ji Young Park, Seon Yong Kwon, Hyuck Hoon Suh, Dae Hun affil: Department of Dermatology, Seoul National University College of Medicine sug: subj: Wound Healing Amnion Occlusive Dressings Laser Therapy Methods Wounds and Injuries Therapy Human Randomized Controlled Trials Prospective Studies Academic Medical Centers South Korea Funding Source Immunohistochemistry Paired T-Tests Data Analysis Software Descriptive Statistics Male Female Adult Adult: 19-44 years Male Female ab: Bovine amniotic membrane ( BAM) has been regarded as an ideal dressing material because it accelerates epithelization and has anti-inflammatory, anti-angiogenic, and strong analgesic effects. To evaluate the clinical effects of BAM and compare them to that of hydrocolloid dressings on wounds created by ablative laser treatments, 49 subjects with nevi or scars requiring ablative laser treatment were evaluated. To compare efficacy, we divided the body into six areas and included patients with two or more similar skin lesions in the same body area. After ablative laser treatments, BAM and hydrocolloid dressing were applied to the wounds with random allocation. Clinical assessments were performed at baseline, 1, 4, 6, 8, 11, and 13 days after treatment. Histologic changes were assessed by skin biopsy. BAM treatment induced faster epithelization than hydrocolloid treatment (6.7 vs. 9.2 days). Erythema and oozing faded more quickly, and the satisfaction score was higher in BAM-treated sites than it was in hydrocolloid-treated sites, without severe adverse effects. Histologic analysis confirmed epithelization and immunohistochemistry revealed different growth factor profiles between the two treatment modalities. BAM benefits wound healing following ablative laser treatment. pubtype: Academic Journal doctype: pictorial research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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