Evaluation of 10-Year Experience of Wegener's Granulomatosis in Iranian Children.

Wegener's granulomatosis or granulomatosis polyangiitis (GPA) is an uncommon chronic systemic vasculitis in children. The aim of this study was to describe pediatric patients with GPA in Iran. We studied records of all patients with GPA diagnosis who were referred to all Iranian Pediatric Rheumatolo...

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Publicado en:ISRN Rheumatology pp. 1 - 5
Autores principales: Tahghighi, Fatemeh, Moradinejad, Mohamad-Hassan, Aghighi, Yahya, Shiari, Reza, Raeeskarami, Seyed-Reza, Salehzadeh, Farhad, Javadi, Vadood, Ziaee, Vahid
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2013
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      pub: Wiley-Blackwell
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        atl: Evaluation of 10-Year Experience of Wegener's Granulomatosis in Iranian Children.
      aug:
        au:
          Tahghighi, Fatemeh
          Moradinejad, Mohamad-Hassan
          Aghighi, Yahya
          Shiari, Reza
          Raeeskarami, Seyed-Reza
          Salehzadeh, Farhad
          Javadi, Vadood
          Ziaee, Vahid
        affil: Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
      sug:
        subj:
          Granulomatosis with Polyangiitis
          Epidemiology
          Symptoms
          Human
          Child
          Iran
          Retrospective Design Utilization
          Medical Records Utilization
          Male
          Female
          Hematologic Tests Utilization
          Child: 6-12 years
          Male
          Female
      ab: Wegener's granulomatosis or granulomatosis polyangiitis (GPA) is an uncommon chronic systemic vasculitis in children. The aim of this study was to describe pediatric patients with GPA in Iran. We studied records of all patients with GPA diagnosis who were referred to all Iranian Pediatric Rheumatology Division from 2002 to 2011. A total of 11 patients (5 females and 6 males) enrolled in this study. In children less than 15 years old, the prevalence of GPA is 0.6 per million. The mean age of GPA diagnosis was 11 years and average delay diagnosis was 20 months. Mortality rate was 18.1% due to pulmonary vasculitis and infection. The most common organ system involvement was upper and lower respiratory tract involvement (81.8% and 63.9%, resp.). Other common manifestations were renal (36.3), skin (27.2%), and eye involvement (18.2%).
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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