Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis.

The claim that circumcision reduces the risk of sexually transmitted infections has been repeated so frequently that many believe it is true. A systematic review and meta-analyses were performed on studies of genital discharge syndrome versus genital ulcerative disease, genital discharge syndrome, n...

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Publicado en:ISRN Urology pp. 1 - 43
Autor principal: Van Howe, Robert S.
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis.
      aug:
        au: Van Howe, Robert S.
        affil: Department of Pediatrics and Human Development, Michigan State University College of Human Medicine, 413 E. Ohio Street, Marquette, MI 49855, USA
      sug:
        subj:
          Sexually Transmitted Diseases
          Circumcision
          Human
          Meta Analysis
          Systematic Review
          Medline
          Papillomaviruses
          Data Analysis Software
          Linear Regression
          Chi Square Test
          HIV Infections
          Odds Ratio
          Confidence Intervals
          Warts, Venereal
      ab: The claim that circumcision reduces the risk of sexually transmitted infections has been repeated so frequently that many believe it is true. A systematic review and meta-analyses were performed on studies of genital discharge syndrome versus genital ulcerative disease, genital discharge syndrome, nonspecific urethritis, gonorrhea, chlamydia, genital ulcerative disease, chancroid, syphilis, herpes simplex virus, human papillomavirus, and contracting a sexually transmitted infection of any type. Chlamydia, gonorrhea, genital herpes, and human papillomavirus are not significantly impacted by circumcision. Syphilis showed mixed results with studies of prevalence suggesting intact men were at great risk and studies of incidence suggesting the opposite. Intact men appear to be of greater risk for genital ulcerative disease while at lower risk for genital discharge syndrome, nonspecific urethritis, genital warts, and the overall risk of any sexually transmitted infection. In studies of general populations, there is no clear or consistent positive impact of circumcision on the risk of individual sexually transmitted infections. Consequently, the prevention of sexually transmitted infections cannot rationally be interpreted as a benefit of circumcision, and any policy of circumcision for the general population to prevent sexually transmitted infections is not supported by the evidence in the medical literature.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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