Fatigue interference with daily living among patients with inflammatory bowel disease.

Purpose: The purpose of the study was to examine fatigue interference with daily living in patients with inflammatory bowel disease (IBD) and to explore relationships between severe fatigue interference and socio-demographic and clinical variables, including use of complementary and alternative medi...

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Publicado en:Quality of Life Research Vol. 23; no. 2; pp. 707 - 718
Autores principales: Opheim, Randi, Fagermoen, May Solveig, Bernklev, Tomm, Jelsness-Jorgensen, Lars-Petter, Moum, Bjorn
Formato: research Journal Article
Publicado: Springer Nature Mar2014
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2014
      vid: 23
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11136-013-0508-4
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        atl: Fatigue interference with daily living among patients with inflammatory bowel disease.
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        au:
          Opheim, Randi
          Fagermoen, May Solveig
          Bernklev, Tomm
          Jelsness-Jorgensen, Lars-Petter
          Moum, Bjorn
        affil: Division of Medicine, Department of Gastroenterology, Oslo University Hospital, Nydalen, P.O. Box 4956, 0424, Oslo, Norway, randi.opheim@medisin.uio.no.
      sug:
        subj:
          Activities of Daily Living
          Fatigue Physiopathology
          Inflammatory Bowel Diseases Physiopathology
          Quality of Life
          Adult
          Aged
          Alternative Therapies
          Cross Sectional Studies
          Fatigue Etiology
          Fatigue Therapy
          Female
          Human
          Inflammatory Bowel Diseases Complications
          Inflammatory Bowel Diseases Therapy
          Logistic Regression
          Male
          Middle Age
          Questionnaires
          Scales
          Young Adult
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: The purpose of the study was to examine fatigue interference with daily living in patients with inflammatory bowel disease (IBD) and to explore relationships between severe fatigue interference and socio-demographic and clinical variables, including use of complementary and alternative medicine (CAM).Methods: Data were collected using self-report questionnaires from adult IBD outpatients. Fatigue interference was assessed with the 5-item Fatigue Severity Scale, and scores ≥ 5 were defined as severe fatigue interference. CAM use was assessed with the International CAM Questionnaire. Multivariate logistic regression analysis was used to examine associations between severe fatigue interference and socio-demographic factors, clinical factors, and CAM use.Results: In total, 428 patients had evaluable questionnaires (response rate 93 %). Severe fatigue interference was reported by 39 % of the total sample. Patients with Crohn's disease (CD) (n = 238) were more likely than patients with ulcerative colitis (UC) (n = 190) to report severe fatigue interference (43 and 33 %, respectively, p = 0.003). In addition, patients reporting severe fatigue interference were more likely to have active disease than patients without severe fatigue interference (p < 0.001 for both diagnoses). Patients with inactive disease had scores comparable to the general population. Factors independently associated with severe fatigue interference in UC included disease activity and CAM use, while in CD they included disease activity and current smoking.Conclusions: Severe fatigue interference is common among IBD patients with active disease. Among patients with UC, but not CD, CAM use was associated with severe fatigue interference. The relationship between fatigue interference and personal factors should be considered further in subsequent studies.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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