The impact of protein supplementation on cognitive performance in frail elderly.
Purpose: Maintenance of cognitive abilities is important for elderly to stay independent. With the aging of the population, the call for modifiable factors is emerging. Dietary protein might improve cognitive performance; however, this has hardly been studied. Therefore, we studied the impact of 24-...
| Publicado en: | European Journal of Nutrition Vol. 53; no. 3; pp. 803 - 813 |
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| Autores principales: | , , , , , , |
| Formato: | equations & formulas research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Apr2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104058657&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104058657 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Apr2014 vid: 53 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104058657 95275564 10.1007/s00394-013-0584-9 NLM24045855 104058657 ppf: 803 ppct: 10 formats: fmt: @attributes: type: P tig: atl: The impact of protein supplementation on cognitive performance in frail elderly. aug: au: Zwaluw, Nikita Rest, Ondine Tieland, Michael Adam, Jos Hiddink, Gert Loon, Luc Groot, Lisette affil: Division of Human Nutrition, Wageningen University, 6700 EV Wageningen The Netherlands sug: subj: Dietary Proteins Administration and Dosage Dietary Supplementation In Old Age Cognition In Old Age Frail Elderly Human Netherlands Funding Source Aged Geriatric Nutrition Randomized Controlled Trials Random Assignment Intervention Trials Treatment Outcomes Neuropsychological Tests Memory In Old Age Attention In Old Age Reaction Time In Old Age Mental Processes In Old Age Prospective Studies Double-Blind Studies Data Collection, Computer Assisted Insulin Blood Diet Records In Old Age Nutritional Assessment In Old Age Body Weights and Measures In Old Age T-Tests Descriptive Statistics Male Female Mathematics Analysis of Covariance Data Analysis Software Aged: 65+ years Male Female ab: Purpose: Maintenance of cognitive abilities is important for elderly to stay independent. With the aging of the population, the call for modifiable factors is emerging. Dietary protein might improve cognitive performance; however, this has hardly been studied. Therefore, we studied the impact of 24-week dietary protein supplementation on cognitive performance in pre-frail and frail elderly people. Methods: Pre-frail and frail elderly subjects, according to the Fried criteria, randomly received a protein drink containing 15 g protein or a placebo drink twice a day. Cognitive performance was measured at baseline and after 24 weeks by means of a sensitive neuropsychological test battery. In addition, reaction time was assessed after both 12 and 24 weeks of intervention. Domain scores were calculated for the domains episodic memory, attention and working memory, information processing speed, and executive functioning. Analyses of covariance were used to determine differences between groups. Linear mixed models were used to determine differences in reaction time over time and per treatment. Results: In total, 65 subjects (79 ± 8 years) with a median Mini-Mental State Examination score of 28 (interquartile range 26-30) were included. Reaction time improved more in the protein group (68 ms) than in the placebo group (18 ms, P = 0.03). Dietary protein had no significant effect on any of the cognitive domain scores. Conclusions: Protein supplementation might improve reaction time performance in pre-frail and frail elderly, but did not improve other cognitive functions. pubtype: Academic Journal doctype: equations & formulas research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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