Early and Late Shift of Brain Laterality in STG, HG, and Cerebellum with Normal Aging during a Short-Term Memory Task.

Evidence suggests that cognitive performance deteriorates in noisy backgrounds and the problems are more pronounced in older people due to brain deficits and changes. The present study used functional MRI (fMRI) to investigate the neural correlates of this phenomenon during short-term memory using a...

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Publicado en:ISRN Neurology pp. 1 - 14
Autores principales: Manan, Hanani Abdul, Yusoff, Ahmad Nazlim, Franz, Elizabeth A., Sarah Mukari, Siti Zamratol-Mai
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        atl: Early and Late Shift of Brain Laterality in STG, HG, and Cerebellum with Normal Aging during a Short-Term Memory Task.
      aug:
        au:
          Manan, Hanani Abdul
          Yusoff, Ahmad Nazlim
          Franz, Elizabeth A.
          Sarah Mukari, Siti Zamratol-Mai
        affil: Diagnostic Imaging & Radiotherapy Program, School of Diagnostic Science & Applied Health, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia
      sug:
        subj:
          Dominance, Cerebral
          Aging
          Memory
          Task Performance and Analysis
          Cerebellum
          Human
          Magnetic Resonance Imaging Methods
          Adult
          Middle Age
          Aged
          Descriptive Statistics
          Analysis of Variance
          Post Hoc Analysis
          Data Analysis Software
          Paired T-Tests
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
      ab: Evidence suggests that cognitive performance deteriorates in noisy backgrounds and the problems are more pronounced in older people due to brain deficits and changes. The present study used functional MRI (fMRI) to investigate the neural correlates of this phenomenon during short-term memory using a forward repeat task performed in quiet (STMQ) and in noise: 5-dB SNR (STMN) on four groups of participants of different ages. The performance of short-term memory tasks was measured behaviourally. No significant difference was found across age groups in STMQ. However, older adults (50-65 year olds) performed relatively poorly on the STMN. fMRI results on the laterality index indicate changes in hemispheric laterality in the superior temporal gyrus (STG), Heschl's gyrus (HG), and cerebellum, and a leftward asymmetry in younger participants which changes to a more rightward asymmetry in older participants. The results also indicate that the onset of the laterality shift varies from one brain region to another. STG and HG show a late shift while the cerebellum shows an earlier shift. The results also reveal that noise influences this shifting. Finally, the results support the hypothesis that functional networks that underlie STG, HG, and cerebellum undergo reorganization to compensate for the neural deficit/cognitive decline.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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