Randomized in vivo trial evaluating plaque inhibition benefits of an advanced stannous-containing sodium fluoride dentifrice used in conjunction with power brush technology.
Objective To compare the plaque inhibition efficacy of a novel stannous-containing sodium fluoride test dentifrice to a standard anticavity negative control dentifrice, when both were used in conjunction with an advanced oscillating-rotating ( O/ R) power toothbrush. Methods This was a randomized, t...
| Published in: | International Journal of Dental Hygiene Vol. 12; no. 2; pp. 89 - 96 |
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| Main Authors: | , , , , , , |
| Format: | clinical trial equations & formulas research tables/charts randomized controlled trial Journal Article |
| Published: |
Wiley-Blackwell
May2014
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104062918&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104062918 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16015029 K8M jtl: International Journal of Dental Hygiene issn: 16015029 maglogo: Y pubinfo: dt: May2014 vid: 12 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104062918 95447825 10.1111/idh.12040 NLM23844867 104062918 ppf: 89 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Randomized in vivo trial evaluating plaque inhibition benefits of an advanced stannous-containing sodium fluoride dentifrice used in conjunction with power brush technology. aug: au: Bellamy, Pg Boulding, A Farmer, S Day, Tn Barker, Ml Harris, R Mussett, Aj affil: Procter & Gamble, Greater London Innovation Center sug: subj: Dental Plaque Prevention and Control Fluorides Therapeutic Use Dentifrices Therapeutic Use Toothbrushes Utilization Human Funding Source In Vivo Studies Toothbrushing Randomized Controlled Trials Double-Blind Studies Male Female Adult Middle Age P-Value Crossover Design Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Objective To compare the plaque inhibition efficacy of a novel stannous-containing sodium fluoride test dentifrice to a standard anticavity negative control dentifrice, when both were used in conjunction with an advanced oscillating-rotating ( O/ R) power toothbrush. Methods This was a randomized, two-treatment, three-period, double-blind crossover study conducted in a population using an O/ R power brush. Subjects brushed twice per day with their assigned dentifrice during the three-treatment periods, each lasting for 17 consecutive days. Each period was separated by a 4-day washout period during which subjects continued to use their O/ R power toothbrush. Plaque levels were assessed and averaged amongst three assessments taken on days 15, 16 and 17 at the end of each treatment period using digital plaque imaging analysis. Assessments were carried out on the facial anterior tooth surfaces in the morning before brushing ( A. M. prebrush) following whole-mouth brushing (30 s per quadrant) with the assigned dentifrice ( A. M. post-brush) and in the afternoon ( P.M.). Results Twenty-seven subjects were randomized and completed the study. During the 17-day usage period, the stannous-containing test Na F dentifrice demonstrated a statistically significant lower mean plaque area versus the negative control dentifrice at each assessment timepoint; overnight A. M. prebrush was 33.8% lower ( P < 0.0001), A. M. post-brush was 21.8% lower ( P < 0.01), and P. M. was 29.2% lower ( P < 0.0001). Conclusion A population of O/ R power toothbrush users had significantly less plaque coverage for all three measurements when using a stannous-containing Na F dentifrice than when using a negative control (fluoride) dentifrice. pubtype: Academic Journal doctype: clinical trial equations & formulas research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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