Partial laryngopharyngectomy in the treatment of squamous cell carcinoma of hypopharynx: Analysis of the oncologic results and laryngeal preservation rate.
Conclusion: Partial laryngopharyngectomy (PLP) provides acceptable oncologic results and laryngeal preservation rate in selected patients with squamous cell carcinoma of the hypopharynx. Even when local recurrence develops, the chance of successful salvage is still high. Objectives: To evaluate the...
| Publicado en: | Acta Oto-Laryngologica Vol. 132; no. 12; pp. 1342 - 1347 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Dec2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104067329&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104067329 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Dec2012 vid: 132 iid: 12 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 104067329 83513178 10.3109/00016489.2012.700122 NLM23050655 104067329 ppf: 1342 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Partial laryngopharyngectomy in the treatment of squamous cell carcinoma of hypopharynx: Analysis of the oncologic results and laryngeal preservation rate. aug: au: Kuo, Yen-ling Chang, Chia-Fan Chang, Shyne-Yih Chu, Pen-Yuan affil: Department of Otolaryngology, National Yang-Ming University Hospital sug: subj: Pharyngectomy Methods Carcinoma, Squamous Cell Surgery Hypopharynx Surgery Larynx Surgery Treatment Outcomes Human Descriptive Statistics Retrospective Design Record Review Male Data Analysis Software Adult Middle Age Aged Chi Square Test Fisher's Exact Test Survival Analysis Funding Source Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male ab: Conclusion: Partial laryngopharyngectomy (PLP) provides acceptable oncologic results and laryngeal preservation rate in selected patients with squamous cell carcinoma of the hypopharynx. Even when local recurrence develops, the chance of successful salvage is still high. Objectives: To evaluate the oncologic results and laryngeal preservation rate in patients with squamous cell carcinoma of the hypopharynx who underwent PLP. Methods: The results of 39 patients who underwent PLP were compared with those of 91 patients who underwent total laryngectomy (TL). Results: The distribution of the primary T stages were 23 (59%) pT2, 9 (23%) pT3, and 7 (18%) pT4; the pathologic stages were 8 patients (21%) stage II, 9 (23%) stage III, and 22 (56%) stage IV. All of the patients also had ipsilateral or bilateral neck dissections. Eighteen patients (46%) received postoperative adjuvant therapy. After a median follow-up of 39 months, 17 patients (44%) had recurrence, including 12 local, 2 regional, and 3 distant lesions. The 5-year overall and disease-specific survival were 44% and 56%, respectively; functional preservation was 62%. The recurrence rate was similar in patients treated with PLP and TL (44% vs 36%, p = 0.431); the local recurrence rate was higher after PLP than after TL (31% vs 8%, p = 0.001). The salvage surgery was successful in four of the six patients (67%). After salvage treatment, the 5-year overall survival (44% vs 47%) and disease-specific survival (56% vs 62%) were similar in the two groups. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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