Greater impulsivity is associated with decreased brain activation in obese women during a delay discounting task.

Impulsivity and poor inhibitory control are associated with higher rates of delay discounting (DD), or a greater preference for smaller, more immediate rewards at the expense of larger, but delayed rewards. Of the many functional magnetic resonance imaging (fMRI) studies of DD, few have investigated...

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Publicado en:Brain Imaging & Behavior Vol. 7; no. 2; pp. 116 - 129
Autores principales: Stoeckel, Luke E, Murdaugh, Donna L, Cox, James E, Cook 3rd, Edwin W, Weller, Rosalyn E, Cook, Edwin W 3rd
Formato: research Journal Article
Publicado: Springer Nature Jun2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Greater impulsivity is associated with decreased brain activation in obese women during a delay discounting task.
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        au:
          Stoeckel, Luke E
          Murdaugh, Donna L
          Cox, James E
          Cook 3rd, Edwin W
          Weller, Rosalyn E
          Cook, Edwin W 3rd
        affil: Department of Psychology, University of Alabama at Birmingham (UAB), CH 415, 1720 2nd Avenue South, Birmingham, AL, 35294-1170, USA, lstoeckel@partners.org.
      sug:
        subj:
          Brain Physiology
          Behavior
          Obesity Physiopathology
          Psychomotor Performance
          Reward
          Adult
          Decision Making
          Mental Processes
          Female
          Magnetic Resonance Imaging
          Middle Age
          Obesity Psychosocial Factors
          Reaction Time Physiology
          Young Adult
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: Impulsivity and poor inhibitory control are associated with higher rates of delay discounting (DD), or a greater preference for smaller, more immediate rewards at the expense of larger, but delayed rewards. Of the many functional magnetic resonance imaging (fMRI) studies of DD, few have investigated the correlation between individual differences in DD rate and brain activation related to DD trial difficulty, with difficult DD trials expected to activate putative executive function brain areas involved in impulse control. In the current study, we correlated patterns of brain activation as measured by fMRI during difficult vs. easy trials of a DD task with DD rate (k) in obese women. Difficulty was defined by how much a reward choice deviated from an individual's 'indifference point', or the point where the subjective preference for an immediate and a delayed reward was approximately equivalent. We found that greater delay discounting was correlated with less modulation of activation in putative executive function brain areas, such as the middle and superior frontal gyri and inferior parietal lobule, in response to difficult compared to easy DD trials. These results support the suggestion that increased impulsivity is associated with deficient functioning of executive function areas of the brain.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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