Development and validation of a pressure-type automated quantitative sensory testing system for point-of-care pain assessment.

Quantitative sensory testing (QST) can provide useful information about the underlying mechanisms involved in chronic pain. However, currently available devices typically employed suffer from operator-dependent effects, or are too cumbersome for routine clinical care. This paper presents the design...

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Published in:Medical & Biological Engineering & Computing Vol. 51; no. 6; pp. 633 - 645
Main Authors: Harte, Steven E, Mitra, Mainak, Ichesco, Eric A, Halvorson, Megan E, Clauw, Daniel J, Shih, Albert J, Kruger, Grant H
Format: research Journal Article
Published: Springer Nature Jun2013
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
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        atl: Development and validation of a pressure-type automated quantitative sensory testing system for point-of-care pain assessment.
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          Harte, Steven E
          Mitra, Mainak
          Ichesco, Eric A
          Halvorson, Megan E
          Clauw, Daniel J
          Shih, Albert J
          Kruger, Grant H
        affil: Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, MI, 48106, USA.
      sug:
        subj:
          Chronic Pain Diagnosis
          Pain Measurement Equipment and Supplies
          Clinical Information Systems
          Adult
          Equipment Design
          Female
          Human
          Middle Age
          Pain Measurement Methods
          Pain Threshold Physiology
          Patient Education Methods
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: Quantitative sensory testing (QST) can provide useful information about the underlying mechanisms involved in chronic pain. However, currently available devices typically employed suffer from operator-dependent effects, or are too cumbersome for routine clinical care. This paper presents the design and initial validation of a novel automated pressure-pain type QST platform, termed the multi-modal automated sensory testing (MAST) system. The MAST configuration presented consists of wireless, hand-held thumbnail pressure stimulators (with circular 10 mm² rubber tips) and graphical touch screen interface devices to manage the QST process and obtain patient feedback. Validation testing of the custom-designed force sensor showed a 1 % error for low forces increasing to 2 % error for larger loads up to 100 N (full-scale). Validation of the controller using three ramp rates (64, 248, and 496 kPa/s) and six pressures (32, 62, 124, 273, 620, and 1116 kPa) showed an overall mean error of 1.7 % for applied stimuli. Clinical evaluation revealed decreased pressure pain thresholds in chronic pain patients (98.07 ± SE 16.34 kPa) compared to pain free, healthy control subjects (259.88 ± SE 33.54 kPa, p = 0.001). The MAST system is portable and produces accurate, repeatable stimulation profiles indicating potential for point-of-care applications.
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    language: English
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