Modeling and analysis of coagulated liver tissue and its interaction with a scalpel blade.

Radiofrequency-assisted methods have been used in hepatectomy--the resection process of removing liver tissue which encapsulates the tumor from the liver organ. A prototype was built to enable smooth surgical transition between radiofrequency ablation and liver resection. There is a lack of literatu...

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Publicado en:Medical & Biological Engineering & Computing Vol. 51; no. 6; pp. 687 - 696
Autores principales: Leong, Florence, Huang, Wei-Hsuan, Chui, Chee-Kong
Formato: research Journal Article
Publicado: Springer Nature Jun2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Modeling and analysis of coagulated liver tissue and its interaction with a scalpel blade.
      aug:
        au:
          Leong, Florence
          Huang, Wei-Hsuan
          Chui, Chee-Kong
        affil: Department of Mechanical Engineering, National University of Singapore, Singapore, Singapore.
      sug:
        subj:
          Catheter Ablation Methods
          Hepatectomy Methods
          Liver Neoplasms Surgery
          Models, Biological
          Animals
          Liver Physiopathology
          Liver Neoplasms Physiopathology
          Stress, Mechanical
          Swine
      ab: Radiofrequency-assisted methods have been used in hepatectomy--the resection process of removing liver tissue which encapsulates the tumor from the liver organ. A prototype was built to enable smooth surgical transition between radiofrequency ablation and liver resection. There is a lack of literature on mechanical properties of radiofrequency-ablated liver tissue and the tool-tissue interaction during cutting. This led to our study on coagulated tissue mechanical properties and modeling of its dynamic interaction with a scalpel blade. A novel mechanical model was proposed to mimic the mechanical behavior of radiofrequency-ablated liver tissue. The model is able to account for the viscoelastic behavior of the ablated tissue in both compression and relaxation tests. Experiments were performed to validate the proposed model. In addition, a knife blade-tissue interaction model is proposed to demonstrate the potential of integrating the proposed model for application in device design.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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