Imaging of the entire cerebrospinal fluid volume with a multistation 3D SPACE MR sequence: feasibility study in patients with hydrocephalus.
Objectives: To evaluate the feasibility of imaging the entire cerebrospinal fluid (CSF) volume using the SPACE MR sequence.Methods: The SPACE sequence encompassing the brain and spine was performed at 1.5 T in 12 healthy volunteers and 26 consecutive patients with hydrocephalus. Image contrast was e...
| Publicado en: | European Radiology Vol. 23; no. 6; pp. 1450 - 1459 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104073563&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104073563 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2013 vid: 23 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104073563 NLM23239062 2012121617 10.1007/s00330-012-2732-7 NLM23239062 104073563 ppf: 1450 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Imaging of the entire cerebrospinal fluid volume with a multistation 3D SPACE MR sequence: feasibility study in patients with hydrocephalus. aug: au: Hodel, Jérôme Lebret, Alain Petit, Eric Leclerc, Xavier Zins, Marc Vignaud, Alexandre Decq, Philippe Rahmouni, Alain affil: Department of Neuroradiology, Hôpital Henri Mondor, Créteil, France, jeromehodel@hotmail.com. sug: subj: Cerebrospinal Fluid Metabolism Hydrocephalus Cerebrospinal Fluid Magnetic Resonance Imaging Methods Tomography, X-Ray Computed Methods Adult Aged Aged, 80 and Over Case Control Studies Discriminant Analysis Pilot Studies Female Human Hydrocephalus Diagnosis Hydrocephalus Pathology Image Processing, Computer Assisted Male Middle Age Regression Meninges Pathology Young Adult Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Objectives: To evaluate the feasibility of imaging the entire cerebrospinal fluid (CSF) volume using the SPACE MR sequence.Methods: The SPACE sequence encompassing the brain and spine was performed at 1.5 T in 12 healthy volunteers and 26 consecutive patients with hydrocephalus. Image contrast was estimated using difference ratios in signal intensity between CSF and its background. Segmentation of CSF was performed using geometrical features and a topological assumption of CSF shapes. Subarachnoid and ventricular CSF space volumes were assessed in volunteers and patients and linear discriminant analysis was performed.Results: Image contrast was 0.94 between the CSF and the brain and 0.90 between the CSF and the spinal cord. According to the phantom study, the accuracy of CSF volume measurement was 98.5 %. A clear distinction between patients and healthy volunteers was obtained using the linear discriminant analysis. Significant linear regression was found in healthy volunteers between ventricular (Vv) and the whole subarachnoid CSF volume (Vs) with Vv = 0.083 Vs.Conclusions: Imaging of the entire CSF volume is feasible in healthy volunteers and patients with hydrocephalus. CSF volume can be obtained on a whole-body scale. This approach may be of use for the diagnosis and follow-up of patients with hydrocephalus.Key Points: • MRI assessment of CSF volume is feasible in healthy volunteers/hydrocephalus patients. • CSF volume can be obtained on a whole-body scale. • The ratio of subarachnoid and ventricular CSF is constant in healthy volunteers. • CSF linear discriminant analysis can distinguish between patients and healthy volunteers. • Entire CSF volume imaging is useful for diagnosing and following hydrocephalus. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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