Shear wave elastography in the evaluation of rejection or recurrent hepatitis after liver transplantation.
Objectives: To determine whether shear wave elastography (SWE) would be useful in evaluating the presence of rejection or recurrent hepatitis for post-liver transplantation (LT) follow-up.Methods: This retrospective study was approved by our Institutional Review Board and informed consent was waived...
| Publicado en: | European Radiology Vol. 23; no. 6; pp. 1729 - 1738 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104073570&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104073570 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2013 vid: 23 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104073570 NLM23300037 2012121628 10.1007/s00330-012-2748-z NLM23300037 104073570 ppf: 1729 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Shear wave elastography in the evaluation of rejection or recurrent hepatitis after liver transplantation. aug: au: Yoon, Jeong Hee Lee, Jae Young Woo, Hyun Sik Yu, Mi Hye Lee, Eun Sun Joo, Ijin Lee, Kyoung Bun Yi, Nam-Joon Lee, Yoon Jin Han, Joon Koo Choi, Byung Ihn affil: Institute of Radiation Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea. sug: subj: Ultrasonography Methods Graft Rejection Hepatitis Diagnosis Liver Pathology Liver Transplantation Methods Adolescence Adult Aged Biopsy Methods Child Female Human Male Middle Age Pressure Recurrence Retrospective Design Biomechanics Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Child: 6-12 years Middle Aged: 45-64 years Female Male ab: Objectives: To determine whether shear wave elastography (SWE) would be useful in evaluating the presence of rejection or recurrent hepatitis for post-liver transplantation (LT) follow-up.Methods: This retrospective study was approved by our Institutional Review Board and informed consent was waived. Two hundred sixteen liver recipients and 37 liver donors received SWE and concurrent liver biopsy. Of the liver recipients, 142 patients underwent SWE > 4 weeks after the LT (group 1) and 74 patients underwent SWE ≤ 4 weeks after the LT (group 2). Liver stiffness (LS) was compared among groups of donor, no rejection, acute rejection and recurrent hepatitis.Results: In group 1, LS was higher in patients with rejection or hepatitis than in patients without rejection or indefinite rejection (12.29 ± 8.13 kPa vs. 6.33 ± 2.10 kPa, respectively, P < 0.001). In group 2, there was no difference in LS between patients with rejection (n = 8) and those without rejection (n = 61; P > 0.05). The liver recipients without rejection or hepatitis in both groups showed significantly higher LS than the liver donors (P < 0.001).Conclusions: SWE may be used as a non-invasive complementary tool to detect rejection or recurrent hepatitis at follow-up > 4 weeks after the LT.Key Points: • Shear wave ultrasound elastography may be useful at follow-up after liver transplantation • Rejection or hepatitis can be predicted >4 weeks after liver transplantation • Normal liver grafts are stiffer than normal liver. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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