Real-time X-ray-based 4D image guidance of minimally invasive interventions.
Objective: A new technology is introduced that enables real-time 4D (three spatial dimensions plus time) X-ray guidance for vascular catheter interventions with acceptable levels of ionising radiation.Methods: The enabling technology is a combination of low-dose tomographic data acquisition with nov...
| Publicado en: | European Radiology Vol. 23; no. 6; pp. 1669 - 1678 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104073581&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104073581 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2013 vid: 23 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104073581 NLM23314598 2012121639 10.1007/s00330-012-2761-2 NLM23314598 104073581 ppf: 1669 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Real-time X-ray-based 4D image guidance of minimally invasive interventions. aug: au: Kuntz, Jan Gupta, Rajiv Schönberg, Stefan O Semmler, Wolfhard Kachelrieß, Marc Bartling, Sönke affil: Department of Medical Physics in Radiology, German Cancer Research Center-DKFZ, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany, j.kuntz@dkfz.de. sug: subj: Tomography, X-Ray Computed Methods Algorithms Angiography Methods Animals Catheters Fluoroscopy Methods Human Radiation Dosage Radiation, Ionizing Radiographic Image Interpretation, Computer-Assisted Specialties, Medical Methods Radiometry Methods Reproducibility of Results Swine Treatment Outcomes X-Rays ab: Objective: A new technology is introduced that enables real-time 4D (three spatial dimensions plus time) X-ray guidance for vascular catheter interventions with acceptable levels of ionising radiation.Methods: The enabling technology is a combination of low-dose tomographic data acquisition with novel compressed sensing reconstruction and use of prior image information. It was implemented in a prototype set-up consisting of a gantry-based flat detector system. In pigs (n = 5) angiographic interventions were simulated. Radiation dosage on a per time base was compared with the "gold standard" of X-ray projection imaging.Results: Contrary to current image guidance methods that lack permanent 4D updates, the spatial position of interventional instruments could be resolved in continuous, spatial 4D guidance; the movement of the guide wire as well as the expansion of stents could be precisely tracked in 3D angiographic road maps. Dose rate was 23.8 μGy/s, similar to biplane standard angiographic fluoroscopy, which has a dose rate of 20.6 μGy/s.Conclusion: Real-time 4D X-ray image-guidance with acceptable levels of radiation has great potential to significantly influence the field of minimally invasive medicine by allowing faster and safer interventions and by enabling novel, much more complex procedures for vascular and oncological minimally invasive therapy.Key Points: • Real-time 4D (three spatial dimensions plus time) angiographic intervention guidance is realistic. • Low-dose tomographic data acquisition with special compressed sensing-based algorithms is enabled. • Compared with 4D CT fluoroscopy, this method reduces radiation to acceptable levels. • Once implemented, vascular interventions may become safer and faster. • More complex intervention approaches may be developed. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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