Using qualitative research to inform development of a diagnostic algorithm for UTI in children.

Background: Diagnostic and prognostic algorithms can help reduce clinical uncertainty. The selection of candidate symptoms and signs to be measured in case report forms (CRFs) for potential inclusion in diagnostic algorithms needs to be comprehensive, clearly formulated and relevant for end users.Ob...

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Publicado en:Family Practice Vol. 30; no. 3; pp. 325 - 332
Autores principales: de Salis, Isabel, Whiting, Penny, Sterne, Jonathan A C, Hay, Alastair D
Formato: research Journal Article
Publicado: Oxford University Press / USA Jun2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Using qualitative research to inform development of a diagnostic algorithm for UTI in children.
      aug:
        au:
          de Salis, Isabel
          Whiting, Penny
          Sterne, Jonathan A C
          Hay, Alastair D
        affil: School of Social and Community Medicine, University of Bristol, Bristol, UK.
      sug:
        subj:
          Algorithms
          Primary Health Care Methods
          Urinary Tract Infections Diagnosis
          Child, Preschool
          Emergency Service
          Female
          Human
          Interviews
          Male
          Qualitative Studies
          Retrospective Design
          Child, Preschool: 2-5 years
          Female
          Male
      ab: Background: Diagnostic and prognostic algorithms can help reduce clinical uncertainty. The selection of candidate symptoms and signs to be measured in case report forms (CRFs) for potential inclusion in diagnostic algorithms needs to be comprehensive, clearly formulated and relevant for end users.Objective: To investigate whether qualitative methods could assist in designing CRFs in research developing diagnostic algorithms. Specifically, the study sought to establish whether qualitative methods could have assisted in designing the CRF for the Health Technology Association funded Diagnosis of Urinary Tract infection in Young children (DUTY) study, which will develop a diagnostic algorithm to improve recognition of urinary tract infection (UTI) in children aged <5 years presenting acutely unwell to primary care.Methods: Qualitative methods were applied using semi-structured interviews of 30 UK doctors and nurses working with young children in primary care and a Children's Emergency Department. We elicited features that clinicians believed useful in diagnosing UTI and compared these for presence or absence and terminology with the DUTY CRF.Results: Despite much agreement between clinicians' accounts and the DUTY CRFs, we identified a small number of potentially important symptoms and signs not included in the CRF and some included items that could have been reworded to improve understanding and final data analysis.Conclusions: This study uniquely demonstrates the role of qualitative methods in the design and content of CRFs used for developing diagnostic (and prognostic) algorithms. Research groups developing such algorithms should consider using qualitative methods to inform the selection and wording of candidate symptoms and signs.
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        Journal Article
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    language: English
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