Colorectal cancer in inflammatory bowel diseases: CT features with pathological correlation.
Purpose: To describe CT features of inflammatory bowel disease (IBD)-related colorectal cancer and correlate the imaging findings with histopathological findings. Materials and Methods: CT imaging findings in 17 patients with IBD-related colorectal cancer were retrospectively evaluated. Imaging find...
| Publicado en: | Abdominal Imaging Vol. 38; no. 3; pp. 421 - 436 |
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| Autores principales: | , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104076093&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104076093 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09428925 O52 jtl: Abdominal Imaging issn: 09428925 maglogo: N pubinfo: dt: Jun2013 vid: 38 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104076093 NLM22878887 2012142931 10.1007/s00261-012-9947-6 NLM22878887 104076093 ppf: 421 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Colorectal cancer in inflammatory bowel diseases: CT features with pathological correlation. aug: au: Hristova, Lora Soyer, Philippe Hoeffel, Christine Marteau, Philippe Oussalah, Abderrahim Lavergne-Slove, Anne Boudiaf, Mourad Dohan, Anthony Laurent, Valérie affil: Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France, lora.hristova@lrb.aphp.fr. sug: subj: Colorectal Neoplasms Complications Colorectal Neoplasms Radiography Inflammatory Bowel Diseases Complications Inflammatory Bowel Diseases Radiography Tomography, X-Ray Computed Adult Aged Colitis, Ulcerative Complications Colitis, Ulcerative Pathology Colitis, Ulcerative Radiography Colorectal Neoplasms Pathology Crohn Disease Complications Crohn Disease Pathology Crohn Disease Radiography Female Human Image Processing, Computer Assisted Inflammatory Bowel Diseases Pathology Male Middle Age Retrospective Design Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: To describe CT features of inflammatory bowel disease (IBD)-related colorectal cancer and correlate the imaging findings with histopathological findings. Materials and Methods: CT imaging findings in 17 patients with IBD-related colorectal cancer were retrospectively evaluated. Imaging findings were correlated with surgical and histopathological findings. Univariate and multivariate analyses explored the relationships between CT and histopathological variables. Results: Two different CT patterns were individualized including clearly visible soft tissue mass (8/17; 47%) (Type 1 tumor) or stenosis with marked circumferential thickening resembling inflammation (9/17; 53%) (Type 2 tumor). At univariate analysis, thickness of tumor-free colorectal wall at CT was greater in Crohn disease (median, 13 mm) than in ulcerative colitis (median, 7 mm) (P = 0.011). Significant association was found between presence of signet ring cells and Type 2 tumor at CT (6/9, 67% P = 0.009) and colonic dilatation proximal to tumor (5/6, 83%; P = 0.035). At multivariate analysis, free-fluid effusion was the single independent CT variable predictive for the presence of signet ring cells (odds ratio = 50; 95% CI 2.56-977.02; P = 0.01). Conclusion: Colorectal cancer in IBD displays two main features on CT. Type 2 tumors and free-fluid effusion correlate with presence of signet ring cells. Knowledge of these findings is critical to help suggest the diagnosis. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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