Effects of Lung Support Formula on respiratory symptoms among older adults: results of a three-month follow-up study in Shanghai, China.

Background: With the acceleration of industrialization in low or middle-income nations, the prevalence of respiratory symptoms among older adults is even more significant now in China. Contemporary treatments using Western medicine, such as anti-inflammatory regimens, may be effective in relieving t...

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Publicado en:Nutrition Journal Vol. 12; pp. 57 - 58
Autores principales: Cai, Yong, Shi, Rong, Song, Huijiang, Shang, Meili, Shen, Tian, Shariff, Mina, Kami, Kenneth, Gu, Pingping, Nguyen, Tuong, Rao, Jianyu
Formato: research randomized controlled trial Journal Article
Publicado: BioMed Central 2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Effects of Lung Support Formula on respiratory symptoms among older adults: results of a three-month follow-up study in Shanghai, China.
      aug:
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          Cai, Yong
          Shi, Rong
          Song, Huijiang
          Shang, Meili
          Shen, Tian
          Shariff, Mina
          Kami, Kenneth
          Gu, Pingping
          Nguyen, Tuong
          Rao, Jianyu
        affil: School of Public Health affiliated with Shanghai Jiaotong University School of Medicine, Shanghai 200025, People's Republic of China. shirong61@yahoo.com.cn.
      sug:
        subj:
          Dietary Supplements
          Drugs, Chinese Herbal Administration and Dosage
          Health Promotion
          Aged
          Antiinflammatory Agents Administration and Dosage
          Bronchitis Drug Therapy
          Bronchitis Physiopathology
          China
          Chronic Disease
          Cough Drug Therapy
          Cough Physiopathology
          Double-Blind Studies
          Dyspnea Drug Therapy
          Dyspnea Physiopathology
          Female
          Prospective Studies
          Human
          Laryngitis Drug Therapy
          Laryngitis Physiopathology
          Lung Drug Effects
          Lung Physiopathology
          Male
          Middle Age
          Pharyngitis Drug Therapy
          Pharyngitis Physiopathology
          Tracheal Diseases Drug Therapy
          Tracheal Diseases Physiopathology
          Treatment Outcomes
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background: With the acceleration of industrialization in low or middle-income nations, the prevalence of respiratory symptoms among older adults is even more significant now in China. Contemporary treatments using Western medicine, such as anti-inflammatory regimens, may be effective in relieving the symptoms, but may have unexpected side effects. Some natural products may be effective in improving respiratory functions, yet their efficacies remain to be examined in randomized, placebo-controlled studies. To evaluate the effects of Lung Support Formula, a nutritional supplement which contains naturally derived Chinese herbal medicines, we conducted a clinical study among older adults in Shanghai, China.Methods: A total of 100 patients over 50 years old were recruited and blindly randomized into the treatment or control group. The subjects took either 1 Lung Support Formula capsule or a placebo capsule twice a day for 12 weeks. All subjects were followed-up every 4 weeks to perform investigative and clinical examinations. Repeated measure of analysis of variance was employed to compare the trend of respiratory symptoms scores between the 2 groups during 12 weeks of follow-up.Results: Fifty patients from the treatment group and 49 patients in the control group completed the 3-month follow-up. No adverse events were reported in the treatment duration. The percentage of patients reported to have chronic cough, chronic expectoration and chronic bronchitis were significantly decreased in the treatment group when compared with baseline after a 3-month intervention (P < 0.05). The respiratory symptoms scores declined gradually with the lapse of time (P < 0.05) in the treatment group and there were no significant changes in the control group by repeated measure of analysis of variance (P > 0.05).Conclusions: The clinical research shows that use of Lung Support Formula shows significant improvements of respiratory symptoms and is well-tolerated in short-term use among older adults. An additional study involving more subjects and longer-term follow-up would be needed to provide convincing evidence of the improvement of respiratory symptoms in the treatment group.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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