Vitamin D analogue TX 527 down-regulates the NF-κB pathway and controls the proliferation of endothelial cells transformed by Kaposi sarcoma herpesvirus.

Background and Purpose: The Kaposi sarcoma (KS)-associated herpesvirus GPCR (vGPCR) is a key molecule in the pathogenesis of KS, where it increases NF-κB gene expression and activates the NF-κB pathway. We investigated whether the less calcemic vitamin D analogue TX 527 inhibited the proliferation o...

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Bibliographic Details

Published in:	British Journal of Pharmacology Vol. 169; no. 7; pp. 1635 - 1646
Main Authors:	González-Pardo, V, Verstuyf, A, Boland, R, Russo de Boland, A
Format:	research Journal Article
Published:	Wiley-Blackwell Aug2013
Online Access:	View this record in EBSCOhost