Microalbuminuria and glomerular filtration rate in paediatric visceral leishmaniasis.

Visceral leishmaniasis, caused by Leishmania donovani, is a serious form of leishmaniasis and fatal if untreated. Nearly half of the VL cases are children. There are very few studies of renal function in pediatric visceral leishmaniasis. The aim of this study was to evaluate renal dysfunction by stu...

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Publicado en:BioMed Research International Vol. 2013; pp. 498918 - 498919
Autores principales: Verma, Neena, Lal, Chandra Shekhar, Rabidas, Vidyanand, Pandey, Krishna, Singh, Dharmendra, Kumar, Sanjay, Verma, Rakesh Bihari, Das, Pradeep
Formato: research Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2013
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Microalbuminuria and glomerular filtration rate in paediatric visceral leishmaniasis.
      aug:
        au:
          Verma, Neena
          Lal, Chandra Shekhar
          Rabidas, Vidyanand
          Pandey, Krishna
          Singh, Dharmendra
          Kumar, Sanjay
          Verma, Rakesh Bihari
          Das, Pradeep
        affil: Rajendra Memorial Research Institute of Medical Sciences (Indian Council of Medical Research), Agam Kuan, Patna 800 007, India.
      sug:
        subj:
          Albuminuria Complications
          Albuminuria Physiopathology
          Glomerular Filtration Rate Physiology
          Leishmaniasis Complications
          Leishmaniasis Physiopathology
          Albuminuria Pathology
          Albuminuria Urine
          Child
          Human
          Leishmaniasis Pathology
          Leishmaniasis Urine
          Child: 6-12 years
      ab: Visceral leishmaniasis, caused by Leishmania donovani, is a serious form of leishmaniasis and fatal if untreated. Nearly half of the VL cases are children. There are very few studies of renal function in pediatric visceral leishmaniasis. The aim of this study was to evaluate renal dysfunction by studying glomerular filtration rate (GFR), microalbuminuria, and microscopic examination of urine. Laboratory analysis was performed on blood and urine samples of 40 parasitologically confirmed pediatric VL cases. Laboratory data of urine examination showed albuminuria in 10% (4/40), white blood cells in 20% (8/40), hematuria in 10% (4/40), microalbuminuria in 37.5% (15/40), and decreased GFR in 27.5% (11/40). Renal involvement was manifested in most of the pediatric VL cases. These findings may help clinicians in decision making for safe and suitable antileishmanial treatment particularly in childhood VL.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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