Alpha-lipoic acid upregulates antioxidant enzyme gene expression and enzymatic activity in diabetic rat kidneys through an O-GlcNAc-dependent mechanism.

Purpose: The combined hyperglycemia lowering and antioxidant actions of α-lipoic acid (LA) contribute to its usefulness in preventing renal injury and other diabetic complications. The precise mechanisms by which LA alters diabetic oxidative renal injury are not known. We hypothesized that LA throug...

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Bibliographic Details

Published in:	European Journal of Nutrition Vol. 52; no. 5; pp. 1461 - 1474
Main Authors:	Arambašić, Jelena, Mihailović, Mirjana, Uskoković, Aleksandra, Dinić, Svetlana, Grdović, Nevena, Marković, Jelena, Poznanović, Goran, Bajec, Djordje, Vidaković, Melita
Format:	pictorial research tables/charts Journal Article
Published:	Springer Nature Aug2013
Online Access:	View this record in EBSCOhost