Effects of framing coil shape, orientation, and thickness on intra-aneurysmal flow.

To study the effects of the geometrical characteristics of a framing coil on aneurysm thromboembolization efficacy, the hemodynamics in lateral aneurysms filled with coils having a different shape, orientation, and thickness were analyzed using computational fluid dynamics. The aneurysms packed with...

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Publicado en:Medical & Biological Engineering & Computing Vol. 51; no. 9; pp. 981 - 991
Autores principales: Jeong, Woowon, Han, Moon Hee, Rhee, Kyehan
Formato: research Journal Article
Publicado: Springer Nature Sep2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Effects of framing coil shape, orientation, and thickness on intra-aneurysmal flow.
      aug:
        au:
          Jeong, Woowon
          Han, Moon Hee
          Rhee, Kyehan
        affil: Department of Mechanical Engineering, Myongji University, 38-2, Namdong, Yongin, 449-728, Kyunggi-do, South Korea.
      sug:
        subj:
          Embolization, Therapeutic Equipment and Supplies
          Cerebral Aneurysm Physiopathology
          Cerebral Aneurysm Therapy
          Models, Biological
          Computer Simulation
          Hemodynamics Physiology
      ab: To study the effects of the geometrical characteristics of a framing coil on aneurysm thromboembolization efficacy, the hemodynamics in lateral aneurysms filled with coils having a different shape, orientation, and thickness were analyzed using computational fluid dynamics. The aneurysms packed with vortex and cage-shaped coils were modeled using three different coil orientations: transverse, parallel, and orthogonal. The orthogonal orientation of a vortex coil and parallel orientation of a cage-shaped coil showed higher inflow, vorticity, and wall shear stress in the dome region, which provide an unfavorable hemodynamic environment for thromboembolization. Thicker coils also produced unfavorable hemodynamic conditions compared to normal coils having the same shape, orientation, and total coil volume. Though the effects of coil shape and orientation on the hemodynamic parameters of interest were not consistent, the open area at the distal half of the mid-transverse plane of an aneurysm showed significant positive correlation with flow into the dome region and mean vorticity in the dome region. Therefore, blocking the distal mid-transverse plane of an aneurysm using coils would effectively reduce the intra-aneurysmal flow activity and provide a more efficient hemodynamic environment for thromboembolization.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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