Checking for completeness of 24-h urine collection using para-amino benzoic acid not necessary in the Observing Protein and Energy Nutrition study.
Background/Objectives:The orally administered para-amino benzoic acid (PABA) is known to have near 100% excretion in urine and is used as a measure of 24-h urine collection completeness (referred to as PABAcheck). The purpose was to examine the effect of including urine collections deemed incomplete...
| Publicado en: | European Journal of Clinical Nutrition Vol. 67; no. 8; pp. 863 - 868 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104086040&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104086040 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09543007 EUC jtl: European Journal of Clinical Nutrition issn: 09543007 maglogo: N pubinfo: dt: Aug2013 vid: 67 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104086040 89595992 2012217810 10.1038/ejcn.2013.62 NLM23486508 104086040 ppf: 863 ppct: 5 formats: tig: atl: Checking for completeness of 24-h urine collection using para-amino benzoic acid not necessary in the Observing Protein and Energy Nutrition study. aug: au: Subar, A F Midthune, D Tasevska, N Kipnis, V Freedman, L S affil: Division of Cancer Control and Population Sciences, US National Cancer Institute, Bethesda, MD, USA. sug: subj: Dietary Proteins Urine Nitrogen Urine Nutritional Assessment Nutritional Status Potassium Compounds Urine Specimen Handling Vitamin B Complex Urine Adult Aged Biological Markers Urine Diet Diet Records Dietary Proteins Administration and Dosage Energy Intake Female Human Male Memory Middle Age Nitrogen Administration and Dosage Potassium Compounds Administration and Dosage Questionnaires Self Report Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Background/Objectives:The orally administered para-amino benzoic acid (PABA) is known to have near 100% excretion in urine and is used as a measure of 24-h urine collection completeness (referred to as PABAcheck). The purpose was to examine the effect of including urine collections deemed incomplete based on PABAcheck in a dietary measurement error study.Subjects/Methods:The Observing Protein and Energy Nutrition (OPEN) study was conducted in 1999-2000 and included 484 men and women aged 40-69 years. A food frequency questionnaire and 24-h dietary recalls were evaluated using recovery biomarkers that included urinary nitrogen and potassium from two 24-h urine collections. Statistical modeling determined the measurement error properties of dietary assessment instruments. In the original analyses, PABAcheck was used as a measure of complete urine collection; incomplete collections were either excluded or adjusted to acceptable levels. The OPEN data were reanalyzed including all urine collections and by using criteria based on self-reported missing voids to assess the differences.Results:Means and coefficients of variation for biomarker-based protein and potassium intakes, and measurement error model-based correlations and attenuation factors were similar regardless of whether PABAcheck or missed voids were considered.Conclusion:PABAcheck may not be required in large population-based biomarker studies. However, until there are more analyses evaluating the necessity of a PABAcheck, it is recommended that PABA be given to all participants, but not necessarily analyzed. Then, PABAcheck could be used selectively as a marker of completeness among the collections in which low levels of biomarker are detected or for which noncompliance is suspected. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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